Yeast Kinome Supplementary Materials

Website Supplementary Table 1 - SAINT Datasets [zip format]

Listing of SAINT interaction data broken into separate files. This archive contains two folders, RAW and FILTERED. RAW contains all the SAINT interactions grouped by TAG with attributes in individual columns delimited by |. FILTERED follows the same format, but only contains interactions with a probability score greater than or equal to 0.85.

Inside the RAW folder, there are four individual files:

  RAW-FLAG - All raw interaction data with the FLAG TAG
  RAW-HA - All raw interaction data with the HA TAG
  RAW-TAP - All raw interaction data with the TAP TAG
  RAW-UNIQUE - All raw interaction data grouped together according to unique BAIT - HIT interactions.

Inside the FILTERED folder, there are four individual files:

  FILTERED-FLAG - All filtered interaction data with the FLAG TAG
  FILTERED-HA - All filtered interaction data with the HA TAG
  FILTERED-TAP - All filtered interaction data with the TAP TAG
  FILTERED-UNIQUE - All filtered interaction data grouped together according to unique BAIT - HIT interactions.

Website Supplementary Table 2 - GO SLIM Process Interactor Overlap [excel format] GO Slim Process Annotation mappings off all Kinase Associated, Kinase Catalytic, Phosphatase Associated, and Phosphatase Catalytic protein interactors in Our Study, LTP, and HTP-HC.

Description of Columns:

  Column A - pk Yorf - Yorf name off all Kinase Associated, Kinase Catalytic, Phosphatase Associated, Phosphatase Catalytic
  Column B - pk Gene - Common name off all Kinase Associated, Kinase Catalytic, Phosphatase Associated, Phosphatase Catalytic
  Column C - pk GO SLIM PROCESS - GO Slim Process of the Phosphatase Protein or Kinase Protein
  Column D - This Study ( >= 0.85 ) Interactors - Every protein that interacts with the Phosphatase Protein or Kinase Protein in column A
  Column E - This Study ( >= 0.85 ) Pooled GO SLIM PROCESS - Pooled all the GO SLIM PROCESS terms for each of the proteins in column D
  Column F and G - Same as C and D but for LTP (Supplementary Table X) interactions
  Column H and I - Same as C and D but for HTP-HC (Supplementary Tabl X) interactions
  Column J - This Study ( >= 0.85 ) - All GO SLIM PROCESS unique to the Saint set
  Column K - LTP - All GO SLIM PROCESS unique to the LC set
  Column L - HTP-HC - All GO SLIM PROCESS unique to the HTP HC set
  Column M - This Study ( >= 0.85 ) intersect LTP - All GO SLIM PROCESS in the intersection of SAINT and LC set
  Column N - This Study ( >= 0.85 ) intersect HTP-HC - All GO SLIM PROCESS in the intersection of SAINT and HTP set
  Column O - LTP n HTP-HC - All GO SLIM PROCESS in the intersection of LC and HTP set
  Column P - This Study ( >= 0.85 ) intersect LTP intersect HTP-HC - All GO SLIM PROCESS in the intersection of SAINT and LC and HTP
  Columns Q - Z - Counts of the GO SLIM PROCESS for each set