The BioGRID ORCS Screen Tab file contains all of the genes and score values associated with a single specific screen. It is a tab-delimited file and the columns contained are outlined below.

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BioGRID ORCS Screen files are denoted by the extension .screen.tab.txt

The first line of a BioGRID ORCS Screen file is the heading line and starts with a hash (#). This line is purely for informational purposes and gives a brief description of the content contained in each column. If you are scripting the use of this file, you can simply ignore it.

The column contents of BioGRID ORCS Screen Files should be as follows:

1. Screen ID - A unique identifier in the BioGRID ORCS database representing this screen. You can match this value with the similarly named value provided in the screen index file
2. Identifier ID - An identifier for the gene represented by the row. This is generally an ENTREZ_GENE ID, but will sometimes contain an alternative ID when the original dataset was ambiguous or we were unable to map the name used by the original authors.
3. Identifier Type - This will be the name of the source database, but can also be AMBIGUOUS or UNKNOWN if we were unable to definitively map the original authors dataset.
4. Official Symbol - The official name for the gene
5. Aliases - List of common aliases for the gene
6. Organism ID - The NCBI Taxonomy ID of the organism used in this screen (example: 9606 for Human)
7. Organism Official - The NCBI official name for the organism used in this screen (example: Homo sapiens for Human)
8. Score.1 - The first score value, the type of score presented will be provided in the screen index file
9. Score.2 - The second score value (if necessary), the type of score presented will be provided in the screen index file
10. Score.3 - The third score value (if necessary), the type of score presented will be provided in the screen index file
11. Score.4 - The fourth score value (if necessary), the type of score presented will be provided in the screen index file
12. Score.5 - The fifth score value (if necessary), the type of score presented will be provided in the screen index file
13. Hit - This will be YES, NO, or N/A to indicate whether or not this gene is considered a “HIT” by the original authors.
14. Source - The source database for the curation of this record. This field will contain BioGRID ORCS when curated by the BioGRID team.

All columns are mandatory so columns with no values are filled with “-“