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orcs:controlled_vocabulary4 [2019/06/27 10:09] (current)
jenn created
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 +====== Screen Format Terms ======
 +^  Term  ^ Description ​      ^
 +^  Pool | Cells are screened in a pooled format and the output is detected via deep sequencing of integrated sgRNAs in the DNA pool. |
 +^  Array  |Cells are screened in an arrayed format requiring high throughput screening technology. May be used to detect phenotypes via automated microscopy or fluorescence/​luminescence. |
 +^  In vivo  | Cells are exposed to an sgRNA library in culture, followed by transplantation into an organism to assess phenotypes in vivo. After a selection phase (e.g., expression of a reporter, outgrowth of a tumor, resistance to therapy), the cells are sequenced to identify enriched and/or depleted sgRNAs . |
 +[[:​orcs:​curation_guide|Back to ORCS Curation Guide]]
orcs/controlled_vocabulary4.txt · Last modified: 2019/06/27 10:09 by jenn