High Throughput Publications in BioGRID

Publications in biogrid with more than 100 interaction evidences are described in the table below. Those which have provided confidence scores or quantifiers for their interactions which have been loaded into BioGRID are indicated in the 'Score' column. For some publications, only a subset of all possible interactions have been loaded, based on a score cut-off suggested by the publication or authors. Where known this cut-off is described in the 'Comments' column.

Pubmed	Author	Year	Species	HTP Interactions(Raw)	Score	Comments
9207794	Fromont-Racine	1997	S.cerevisiae	167 Two-hybrid	No
10688190	Uetz	2000	S.cerevisiae	875 Two-hybrid	No
10900456	Fromont-Racine	2000	S.cerevisiae	266 Two-hybrid	No
11063675	Finger	2000	S.cerevisiae	133 Synthetic Lethality	No
11087867	Newman	2000	S.cerevisiae	177 Two-hybrid	No
11283351	Ito	2001	S.cerevisiae	1585 Two-hybrid	No	As of BioGRID v2.0.29, only interactions with >2 IST hits (Table1) were loaded
11387327	Allen	2001	S.cerevisiae	125 Affinity Capture-MS	No
11489916	Drees	2001	S.cerevisiae	205 Two-hybrid	No
11743162	Tong	2002	S.cerevisiae	232 Two-hybrid	No
11743205	Tong	2001	S.cerevisiae	338 Synthetic Lethality	No
11805826	Gavin	2002	S.cerevisiae	3400 Affinity Capture-MS	No
11805837	Ho	2002	S.cerevisiae	3666 Affinity Capture-MS	No
11884590	Ohi	2002	S.cerevisiae	161 Affinity Capture-MS	No
12052880	Sanders	2002	S.cerevisiae	480 Affinity Capture-MS	No
12150911	Grandi	2002	S.cerevisiae	509 Affinity Capture-MS	No
12374754	Nissan	2002	S.cerevisiae	148 Affinity Capture-MS	No
12556496	Lindstrom	2003	S.cerevisiae	109 Affinity Capture-MS	No
12872131	Peng	2003	S.cerevisiae	109 Affinity Capture-MS	No
14574415	Ubersax	2003	S.cerevisiae	369 Biochemical Activity	No
14660704	Graumann	2004	S.cerevisiae	478 Affinity Capture-MS	No
14690591	Hazbun	2003	S.cerevisiae	151 Affinity Capture-MS	No
14690608	Krogan	2003	S.cerevisiae	673 Synthetic Lethality	No
14729968	Krogan	2003	S.cerevisiae	122 Affinity Capture-MS	No
14759368	Krogan	2003	S.cerevisiae	890 Affinity Capture-MS	No
14764870	Tong	2004	S.cerevisiae	3873 Synthetic Lethality	No
15166135	Lesage	2004	S.cerevisiae	191 Synthetic Lethality	No
15292183	Panse	2004	S.cerevisiae	122 Affinity Capture-MS	No
15353583	Krogan	2004	S.cerevisiae	244 Synthetic Lethality	No
15525520	Pan	2004	S.cerevisiae	180 Synthetic Lethality;135 Synthetic Growth Defect	No
15563457	Kong	2005	S.cerevisiae	112 Synthetic Lethality	No
15590687	Hannich	2005	S.cerevisiae	145 Affinity Capture-MS	No
15657441	Ingvarsdottir	2005	S.cerevisiae	94 Synthetic Lethality;46 Affinity Capture-MS	No
15715908	Lesage	2005	S.cerevisiae	305 Synthetic Lethality	No
15725626	Loeillet	2005	S.cerevisiae	127 Synthetic Lethality	No
15741174	Lutzmann	2005	S.cerevisiae	145 Affinity Capture-MS	No
15766533	Zhao	2005	S.cerevisiae	272 Synthetic Lethality;131 Affinity Capture-MS; 84 Two-hybrid	No
15879519	Millson	2005	S.cerevisiae	124 Two-hybrid	No
16093310	Miller	2005	S.cerevisiae	1977 Two-hybrid	No
16118188	Milgrom	2005	S.cerevisiae	107 Synthetic Lethality	No
16155567	Davierwala	2005	S.cerevisiae	564 Synthetic Lethality	No
16157669	Daniel	2006	S.cerevisiae	204 Synthetic Lethality	No
16172405	Measday	2005	S.cerevisiae	42 Synthetic Lethality;175 Synthetic Growth Defect	No
16269340	Schuldiner	2005	S.cerevisiae	5402 Phenotypic Enhancement;1430 Phenotypic Suppression	Yes
16319894	Ptacek	2005	S.cerevisiae	4183 Biochemical Activity	No
16429126	Gavin	2006	S.cerevisiae	7592 Affinity Capture-MS	No
16476776	Frazier	2006	S.cerevisiae	96 Affinity Capture-MS	No
16487579	Pan	2006	S.cerevisiae	1010 Synthetic Lethality;4317 Synthetic Growth Defect	No
16554755	Krogan	2006	S.cerevisiae	7079 Affinity Capture-MS	No
16729061	Ye	2005	S.cerevisiae	111 Synthetic Lethality;179 Synthetic Growth Defect	No
17167106	Haarer	2007	S.cerevisiae	201 Synthetic Haploinsufficiency	No
17200106	Collins	2007	S.cerevisiae	9064 Affinity Capture-MS	Yes	Computationally derived; loaded only those identified as high confidence by author
17314980	Collins	2007	S.cerevisiae	11606 Phenotypic Enhancement;2815 Phenotypic Suppression	Yes
17507646	Aronova	2007	S.cerevisiae	102 Co-fractionation	No
17634282	Wong	2007	S.cerevisiae	604 Two-hybrid	No	Only multiple screen hits loaded.
17922018	Oeffinger	2007	S.cerevisiae	335 Affinity Capture-MS; 40 Affinity Capture-RNA	No
17923092	McClellan	2007	S.cerevisiae	1414 Synthetic Growth Defect	No	Chemical-Genetic interactions
18194531	SchÃ¶ner	2008	S.cerevisiae	268 Synthetic Lethality	No
18212056	Mitchel	2008	S.cerevisiae	42 Synthetic Lethality;234 Synthetic Growth Defect;34 Affinity Capture-MS	No
18408161	Decourty	2008	S.cerevisiae	169 Synthetic Growth Defect; 34 Affinity Capture-MS	No
18458063	Fillingham	2008	S.cerevisiae	154 Synthetic Growth Defect	No
18467557	Tarassov	2008	S.cerevisiae	2616 PCA	No
18511909	Dekker	2008	S.cerevisiae	109 Affinity Capture-MS; 70 Synthetic Lethality	No
18627629	Logan	2008	S.cerevisiae	114 Synthetic Lethality; 110 Synthetic Growth Defect	No
18667435	Colomina	2008	S.cerevisiae	317 Protein-RNA	No
18676811	Lin	2008	S.cerevisiae	772 Synthetic Lethality; 1720 Synthetic Growth Defect; 102 Synthetic Rescue	No
18719252	Yu	2008	S.cerevisiae	1778 Two-hybrid	No
18780730	Sinha	2008	S.cerevisiae	988 Synthetic Growth Defect	No
18805955	Hasegawa	2008	S.cerevisiae	1092 Affinity Capture-RNA	No
18845848	Addinall	2008	S.cerevisiae	20 Synthetic Lethality; 126 Synthetic Growth Defect; 240 Synthetic Rescue	No
19061648	Wilmes	2008	S.cerevisiae	3803 Phenotypic Enhancement;2655 Phenotypic Suppression	Yes
19269370	Fiedler	2009	S.cerevisiae	2642 Phenotypic Enhancement;1409 Phenotypic Suppression	Yes
19536198	Gong	2009	S.cerevisiae	1420 Affinity Capture-MS	Yes	The authors note that 21,687 interactions were identified as high confidence based on experimental scores and the distribution of scores in reference databases. Only 1420 high confidence interactions were submitted to BioGRID by the authors because they met the additional criteria of containing reciprocal interactors in terms of the bait-prey relationship.
18818364	Roguev	2008	S.pombe	5769 Phenotypic Enhancement;1811 Phenotypic Suppression	Yes
18931302	Dixon	2008	S.pombe	670 Synthetic Growth Defect	No
14704431	Li	2004	C.elegans	4422 Two-hybrid	No	Core and non-core interactions loaded
16845399	Lehner	2006	C.elegans	336 Phenotypic Enhancement	No	RNAi knock down combined with mutation
17417969	Ceron	2007	C.elegans	518 Phenotypic Enhancement	No	RNAi knock down combined with mutation
17897480	Byrne	2007	C.elegans	1251 Phenotypic Enhancement	No	RNAi knock down combined with mutation
8722784	Karim	1996	D.melanogaster	53 Phenotypic Enhancement; 50 Phenotypic Suppression	No
9883586	Maixner	1998	D.melanogaster	9 Phenotypic Enhancement; 128 Phenotypic Suppression	No
11901120	PeÃ±a-Rangel	2002	D.melanogaster	97 Phenotypic Enhancement; 40 Phenotypic Suppression	No
14605208	Giot	2003	D.melanogaster	20193 Two-hybrid	No
15575970	Stanyon	2004	D.melanogaster	1769 Two-hybrid	No
12795696	Risseeuw	2003	A.thaliana	128 Two-hybrid	No
15781858	Hackbusch	2005	A.thaliana	177 Two-hybrid	No
15805477	de Folter	2005	A.thaliana	263 Two-hybrid	No
18642946	Dortay	2008	A.thaliana	156 Two-hybrid	No
12614612	Kneissl	2003	H.sapiens	149 Two-hybrid; 13 Affinity Capture-Western	No
14743216	Bouwmeester	2004	H.sapiens	115 Affinity Capture-MS	No	Only interactions described as high confidence by author were loaded
15175163	Sato	2004	H.sapiens	250 Affinity Capture-MS	No
15231747	Lehner	2004	H.sapiens	129 Two-hybrid	No
15761153	Barrios-Rodiles	2005	H.sapiens	393 Affinity Capture-Luminescence	No	All interactions with LIR >3 from Table S2 were loaded
16169070	Stelzl	2005	H.sapiens	2527 Two-hybrid	No	Interactions described by author as Medium and High quality were loaded
16189514	Rual	2005	H.sapiens	2744 Two-hybrid; 111 Affinity Capture-Western	No
17353931	Ewing	2007	H.sapiens	2068 Two-hybrid	Yes
18782753	Goudreault	2009	H.sapiens	288 Affinity Capture-MS ; 20 Affinity Capture-Western	No
19690564	van Wijk	2009	H.sapiens	346 Two-hybrid	No	LL set identified by authors as high confidence
19549727	Markson	2009	H.sapiens	557 Two-hybrid	Yes	Interactions with scores 4 and 5 identified by authors as high confidence
20098747	Fenner	2010	H.sapiens	108 Reconstituted Complex; 6 Two-hybrid; 6 Affinity Capture-Western	No