High Throughput Publications in BioGRID

Publications in biogrid with more than 100 interaction evidences are described in the table below. Those which have provided confidence scores or quantifiers for their interactions which have been loaded into BioGRID are indicated in the 'Score' column. For some publications, only a subset of all possible interactions have been loaded, based on a score cut-off suggested by the publication or authors. Where known this cut-off is described in the 'Comments' column.

PubmedAuthorYearSpeciesHTP Interactions(Raw)ScoreComments
9207794Fromont-Racine1997S.cerevisiae167 Two-hybridNo
10688190Uetz2000S.cerevisiae875 Two-hybridNo
10900456Fromont-Racine2000S.cerevisiae266 Two-hybridNo
11063675Finger2000S.cerevisiae133 Synthetic LethalityNo
11087867Newman2000S.cerevisiae177 Two-hybridNo
11283351Ito2001S.cerevisiae1585 Two-hybridNoAs of BioGRID v2.0.29, only interactions with >2 IST hits (Table1) were loaded
11387327Allen2001S.cerevisiae125 Affinity Capture-MSNo
11489916Drees2001S.cerevisiae205 Two-hybridNo
11743162Tong2002S.cerevisiae232 Two-hybridNo
11743205Tong2001S.cerevisiae338 Synthetic LethalityNo
11805826Gavin2002S.cerevisiae3400 Affinity Capture-MSNo
11805837Ho2002S.cerevisiae3666 Affinity Capture-MSNo
11884590Ohi2002S.cerevisiae161 Affinity Capture-MSNo
12052880Sanders2002S.cerevisiae480 Affinity Capture-MSNo
12150911Grandi2002S.cerevisiae509 Affinity Capture-MSNo
12374754Nissan2002S.cerevisiae148 Affinity Capture-MSNo
12556496Lindstrom2003S.cerevisiae109 Affinity Capture-MSNo
12872131Peng2003S.cerevisiae109 Affinity Capture-MSNo
14574415Ubersax2003S.cerevisiae369 Biochemical ActivityNo
14660704Graumann2004S.cerevisiae478 Affinity Capture-MSNo
14690591Hazbun2003S.cerevisiae151 Affinity Capture-MSNo
14690608Krogan2003S.cerevisiae673 Synthetic LethalityNo
14729968Krogan2003S.cerevisiae122 Affinity Capture-MSNo
14759368Krogan2003S.cerevisiae890 Affinity Capture-MSNo
14764870Tong2004S.cerevisiae3873 Synthetic LethalityNo
15166135Lesage2004S.cerevisiae191 Synthetic LethalityNo
15292183Panse2004S.cerevisiae122 Affinity Capture-MSNo
15353583Krogan2004S.cerevisiae244 Synthetic LethalityNo
15525520Pan2004S.cerevisiae180 Synthetic Lethality;135 Synthetic Growth DefectNo
15563457Kong2005S.cerevisiae112 Synthetic LethalityNo
15590687Hannich2005S.cerevisiae145 Affinity Capture-MSNo
15657441Ingvarsdottir2005S.cerevisiae94 Synthetic Lethality;46 Affinity Capture-MSNo
15715908Lesage2005S.cerevisiae305 Synthetic LethalityNo
15725626Loeillet2005S.cerevisiae127 Synthetic LethalityNo
15741174Lutzmann2005S.cerevisiae145 Affinity Capture-MSNo
15766533Zhao2005S.cerevisiae272 Synthetic Lethality;131 Affinity Capture-MS; 84 Two-hybridNo
15879519Millson2005S.cerevisiae124 Two-hybridNo
16093310Miller2005S.cerevisiae1977 Two-hybridNo
16118188Milgrom2005S.cerevisiae107 Synthetic LethalityNo
16155567Davierwala2005S.cerevisiae564 Synthetic LethalityNo
16157669Daniel2006S.cerevisiae204 Synthetic LethalityNo
16172405Measday2005S.cerevisiae42 Synthetic Lethality;175 Synthetic Growth DefectNo
16269340Schuldiner2005S.cerevisiae5402 Phenotypic Enhancement;1430 Phenotypic SuppressionYes
16319894Ptacek2005S.cerevisiae4183 Biochemical ActivityNo
16429126Gavin2006S.cerevisiae7592 Affinity Capture-MSNo
16476776Frazier2006S.cerevisiae96 Affinity Capture-MSNo
16487579Pan2006S.cerevisiae1010 Synthetic Lethality;4317 Synthetic Growth DefectNo
16554755Krogan2006S.cerevisiae7079 Affinity Capture-MSNo
16729061Ye2005S.cerevisiae111 Synthetic Lethality;179 Synthetic Growth DefectNo
17167106Haarer2007S.cerevisiae201 Synthetic HaploinsufficiencyNo
17200106Collins2007S.cerevisiae9064 Affinity Capture-MSYesComputationally derived; loaded only those identified as high confidence by author
17314980Collins2007S.cerevisiae11606 Phenotypic Enhancement;2815 Phenotypic SuppressionYes
17507646Aronova2007S.cerevisiae102 Co-fractionationNo
17634282Wong2007S.cerevisiae604 Two-hybridNoOnly multiple screen hits loaded.
17922018Oeffinger2007S.cerevisiae335 Affinity Capture-MS; 40 Affinity Capture-RNA No
17923092McClellan2007S.cerevisiae1414 Synthetic Growth DefectNoChemical-Genetic interactions
18194531Schöner2008S.cerevisiae268 Synthetic LethalityNo
18212056Mitchel2008S.cerevisiae42 Synthetic Lethality;234 Synthetic Growth Defect;34 Affinity Capture-MS No
18408161Decourty2008S.cerevisiae169 Synthetic Growth Defect; 34 Affinity Capture-MSNo
18458063Fillingham2008S.cerevisiae154 Synthetic Growth DefectNo
18467557Tarassov2008S.cerevisiae2616 PCANo
18511909Dekker 2008S.cerevisiae109 Affinity Capture-MS; 70 Synthetic LethalityNo
18627629Logan2008S.cerevisiae114 Synthetic Lethality; 110 Synthetic Growth DefectNo
18667435Colomina2008S.cerevisiae317 Protein-RNANo
18676811Lin2008S.cerevisiae772 Synthetic Lethality; 1720 Synthetic Growth Defect; 102 Synthetic RescueNo
18719252Yu2008S.cerevisiae1778 Two-hybridNo
18780730Sinha2008S.cerevisiae988 Synthetic Growth DefectNo
18805955Hasegawa2008S.cerevisiae1092 Affinity Capture-RNANo
18845848Addinall2008S.cerevisiae20 Synthetic Lethality; 126 Synthetic Growth Defect; 240 Synthetic RescueNo
19061648Wilmes2008S.cerevisiae3803 Phenotypic Enhancement;2655 Phenotypic SuppressionYes
19269370Fiedler2009S.cerevisiae2642 Phenotypic Enhancement;1409 Phenotypic SuppressionYes
19536198Gong2009S.cerevisiae1420 Affinity Capture-MSYesThe authors note that 21,687 interactions were identified as high confidence based on experimental scores and the distribution of scores in reference databases. Only 1420 high confidence interactions were submitted to BioGRID by the authors because they met the additional criteria of containing reciprocal interactors in terms of the bait-prey relationship.
18818364Roguev2008S.pombe5769 Phenotypic Enhancement;1811 Phenotypic SuppressionYes
18931302Dixon2008S.pombe670 Synthetic Growth DefectNo
14704431Li2004C.elegans4422 Two-hybridNoCore and non-core interactions loaded
16845399Lehner2006C.elegans336 Phenotypic EnhancementNo RNAi knock down combined with mutation
17417969Ceron2007C.elegans518 Phenotypic EnhancementNo RNAi knock down combined with mutation
17897480Byrne2007C.elegans1251 Phenotypic EnhancementNo RNAi knock down combined with mutation
8722784Karim1996D.melanogaster53 Phenotypic Enhancement; 50 Phenotypic SuppressionNo
9883586Maixner1998D.melanogaster9 Phenotypic Enhancement; 128 Phenotypic SuppressionNo
11901120Peña-Rangel2002D.melanogaster97 Phenotypic Enhancement; 40 Phenotypic SuppressionNo
14605208Giot2003D.melanogaster20193 Two-hybridNo
15575970Stanyon2004D.melanogaster1769 Two-hybridNo
12795696Risseeuw2003A.thaliana128 Two-hybridNo
15781858Hackbusch2005A.thaliana177 Two-hybridNo
15805477de Folter2005A.thaliana263 Two-hybridNo
18642946Dortay2008A.thaliana156 Two-hybridNo
12614612Kneissl2003H.sapiens149 Two-hybrid; 13 Affinity Capture-Western No
14743216Bouwmeester2004H.sapiens115 Affinity Capture-MS NoOnly interactions described as high confidence by author were loaded
15175163Sato2004H.sapiens250 Affinity Capture-MS No
15231747Lehner2004H.sapiens129 Two-hybrid No
15761153Barrios-Rodiles2005H.sapiens393 Affinity Capture-LuminescenceNoAll interactions with LIR >3 from Table S2 were loaded
16169070Stelzl2005H.sapiens2527 Two-hybrid NoInteractions described by author as Medium and High quality were loaded
16189514Rual2005H.sapiens2744 Two-hybrid; 111 Affinity Capture-WesternNo
17353931Ewing2007H.sapiens2068 Two-hybridYes
18782753Goudreault2009H.sapiens288 Affinity Capture-MS ; 20 Affinity Capture-WesternNo
19690564van Wijk2009H.sapiens346 Two-hybridNoLL set identified by authors as high confidence
19549727Markson2009H.sapiens557 Two-hybridYesInteractions with scores 4 and 5 identified by authors as high confidence
20098747Fenner2010H.sapiens108 Reconstituted Complex; 6 Two-hybrid; 6 Affinity Capture-WesternNo
 
highthroughput.txt · Last modified: 2016/10/13 22:59 (external edit)