High throughput screens
As well as small-scale curated experiments, BioGRID contains data from papers reporting high throughput screens. Since the experimental setup of high throughput screens for interactions can be adjusted to give variable numbers of “hits”, it is common for publications to report a confidence score for each interaction. Before loading any high throughput data into BioGRID the data is assessed and interactions considered low confidence by the authors are not loaded. Generally, the confidence score used by the author is loaded, and on BioGRID gene pages containing interactions from that publication the scores can be displayed by choosing the publication from the “Displaying:” drop-down list. In addition, the number of interactions in BioGRID for each publication is displayed next to that publication.