Preliminary Report - ID Mapping
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| ^ Custom ID ^ DOI ^ AUTHOR ^ DATASET ^ | ^ Custom ID ^ DOI ^ AUTHOR ^ DATASET ^ | ||
| - | | **888800000002** | **[[https://doi.org/10.1101/2020.03.29.20041962|10.1101/2020.03.29.20041962]]** | Gao T (2020) | **[[https://thebiogrid.org/221112/publication|Highly pathogenic coronavirus N protein aggravates lung i | + | | **888800000002** | **[[https://doi.org/10.1101/2020.03.29.20041962|10.1101/2020.03.29.20041962]]** | Gao T (2020) | **[[https://thebiogrid.org/221112/publication|Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation]]** | |
| - | njury by MASP-2-mediated complement over-activation]]** | | + | | **888800000003** | **[[https://doi.org/10.1101/2020.02.16.951723|10.1101/2020.02.16.951723]]** | Sun C (2020) | **[[https://thebiogrid.org/221178/publication|SARS-CoV-2 and SARS-CoV Spike-RBD Structure and Receptor Binding Comparison and Potential Implications on Neutralizing Antibody and Vaccine Development]]** | |
| - | | **888800000003** | **[[https://doi.org/10.1101/2020.02.16.951723|10.1101/2020.02.16.951723]]** | Sun C (2020) | **[[https://thebiogrid.org/221178/publication|SARS-CoV-2 and SARS-CoV Spike-RBD Structure and Receptor Bind | + | | **888800000005** | **[[https://doi.org/10.1101/2020.03.14.988345|10.1101/2020.03.14.988345]]** | Wang K (2020) | **[[https://thebiogrid.org/221183/publication|SARS-CoV-2 invades host cells via a novel route: CD147-spike protein]]** | |
| - | ing Comparison and Potential Implications on Neutralizing Antibody and Vaccine Development]]** | | + | | **888800000006** | **[[https://doi.org/10.1101/2020.02.17.951848|10.1101/2020.02.17.951848]]** | Zhou Q (2020) | **[[https://thebiogrid.org/221185/publication|Structure of dimeric full-length human ACE2 in complex with B0AT1]]** | |
| - | | **888800000005** | **[[https://doi.org/10.1101/2020.03.14.988345|10.1101/2020.03.14.988345]]** | Wang K (2020) | **[[https://thebiogrid.org/221183/publication|SARS-CoV-2 invades host cells via a novel route: CD147-spike | + | | **888800000007** | **[[https://doi.org/10.1101/2020.02.26.964882|10.1101/2020.02.26.964882]]** | Jin Z (2020) | **[[https://thebiogrid.org/221186/publication|Structure of Mpro from COVID-19 virus and discovery of its inhibitors [DEPRECATED PUBLICATION]]]** | |
| - | protein]]** | | + | | **888800000008** | **[[https://doi.org/10.1101/2020.03.29.013490|10.1101/2020.03.29.013490]]** | Wang C (2020) | **[[https://thebiogrid.org/221195/publication|Lectin-like Intestinal Defensin Inhibits 2019-nCoV Spike binding to ACE2]]** | |
| - | | **888800000006** | **[[https://doi.org/10.1101/2020.02.17.951848|10.1101/2020.02.17.951848]]** | Zhou Q (2020) | **[[https://thebiogrid.org/221185/publication|Structure of dimeric full-length human ACE2 in complex with | + | | **888800000009** | **[[https://doi.org/10.1101/2020.03.25.996348|10.1101/2020.03.25.996348]]** | Dai W (2020) | **[[https://thebiogrid.org/221196/publication|Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease]]** | |
| - | B0AT1]]** | | + | | **888800000010** | **[[https://doi.org/10.1101/2020.03.15.992883|10.1101/2020.03.15.992883]]** | Joyce MG (2020) | **[[https://thebiogrid.org/221197/publication|A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein]]** | |
| - | | **888800000007** | **[[https://doi.org/10.1101/2020.02.26.964882|10.1101/2020.02.26.964882]]** | Jin Z (2020) | **[[https://thebiogrid.org/221186/publication|Structure of Mpro from COVID-19 virus and discovery of its in | + | | **888800000011** | **[[https://doi.org/10.1101/2020.03.16.993386|10.1101/2020.03.16.993386]]** | Gao Y (2020) | **[[https://thebiogrid.org/221198/publication|Structure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug target]]** | |
| - | hibitors [DEPRECATED PUBLICATION]]]** | | + | | **888800000012** | **[[https://doi.org/10.1101/2020.03.31.019216|10.1101/2020.03.31.019216]]** | Liang Q (2020) | **[[https://thebiogrid.org/221199/publication|Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis]]** | |
| - | | **888800000008** | **[[https://doi.org/10.1101/2020.03.29.013490|10.1101/2020.03.29.013490]]** | Wang C (2020) | **[[https://thebiogrid.org/221195/publication|Lectin-like Intestinal Defensin Inhibits 2019-nCoV Spike bin | + | | **888800000013** | **[[https://doi.org/10.1101/2020.04.15.042085|10.1101/2020.04.15.042085]]** | Bestle D (2020) | **[[https://thebiogrid.org/221402/publication|TMPRSS2 and furin are both essential for proteolytic activation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets]]** | |
| - | ding to ACE2]]** | | + | | **888800000016** | **[[https://doi.org/10.1101/2020.04.14.042010|10.1101/2020.04.14.042010]]** | Chi X (2020) | **[[https://thebiogrid.org/221405/publication|Humanized Single Domain Antibodies Neutralize SARS-CoV-2 by Targeting Spike Receptor Binding Domain]]** | |
| - | | **888800000009** | **[[https://doi.org/10.1101/2020.03.25.996348|10.1101/2020.03.25.996348]]** | Dai W (2020) | **[[https://thebiogrid.org/221196/publication|Structure-Based Design, Synthesis and Biological Evaluation o | + | | **888800000018** | **[[https://doi.org/10.1101/2020.04.19.049643|10.1101/2020.04.19.049643]]** | Zeng X (2020) | **[[https://thebiogrid.org/221566/publication|Blocking antibodies against SARS-CoV-2 RBD isolated from a phage display antibody library using a competitive biopanning strategy]]** | |
| - | f Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease]]** | | + | | **888800000019** | **[[https://doi.org/10.1101/2020.04.23.057265|10.1101/2020.04.23.057265]]** | Peng Q (2020) | **[[https://thebiogrid.org/221567/publication|Structural and biochemical characterization of nsp12-nsp7-nsp8 core polymerase complex from COVID-19 virus]]** | |
| - | | **888800000010** | **[[https://doi.org/10.1101/2020.03.15.992883|10.1101/2020.03.15.992883]]** | Joyce MG (2020) | **[[https://thebiogrid.org/221197/publication|A Cryptic Site of Vulnerability on the Receptor Binding Do | + | | **888800000020** | **[[https://doi.org/10.1101/2020.04.22.046565|10.1101/2020.04.22.046565]]** | Liu Y (2020) | **[[https://thebiogrid.org/221568/publication|Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals Broad Potential Host Range of SARS-CoV-2]]** | |
| - | main of the SARS-CoV-2 Spike Glycoprotein]]** | | + | | **888800000021** | **[[https://doi.org/10.1101/2020.04.21.053017|10.1101/2020.04.21.053017]]** | Walker A (2020) | **[[https://thebiogrid.org/221569/publication|Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases]]** | |
| - | | **888800000011** | **[[https://doi.org/10.1101/2020.03.16.993386|10.1101/2020.03.16.993386]]** | Gao Y (2020) | **[[https://thebiogrid.org/221198/publication|Structure of RNA-dependent RNA polymerase from 2019-nCoV, a m | + | | **888800000022** | **[[https://doi.org/10.1101/2020.04.17.047498|10.1101/2020.04.17.047498]]** | Rosas Lemus M (2020) | **[[https://thebiogrid.org/221570/publication|The crystal structure of nsp10-nsp16 heterodimer from SARS CoV-2in complex with S-adenosylmethionine]]** | |
| - | ajor antiviral drug target]]** | | + | | **888800000025** | **[[https://doi.org/10.1101/2020.04.29.068890|10.1101/2020.04.29.068890]]** | Rut W (2020) | **[[https://thebiogrid.org/221777/publication|Activity profiling of SARS-CoV-2-PLpro protease provides structural framework for anti-COVID-19 drug design]]** | |
| - | | **888800000012** | **[[https://doi.org/10.1101/2020.03.31.019216|10.1101/2020.03.31.019216]]** | Liang Q (2020) | **[[https://thebiogrid.org/221199/publication|Virus-host interactome and proteomic survey of PMBCs from C | + | | **888800000029** | **[[https://doi.org/10.1101/2020.05.02.20086876|10.1101/2020.05.02.20086876]]** | Zhang D (2020) | **[[https://thebiogrid.org/221831/publication|Ultra-fast and onsite interrogation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in environmental specimens via surface enhanced Raman scattering (SERS)]]** | |
| - | OVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis]]** | | + | | **888800000031** | **[[https://doi.org/10.1101/2020.05.06.079830|10.1101/2020.05.06.079830]]** | Zha L (2020) | **[[https://thebiogrid.org/221833/publication|Development of a COVID-19 vaccine based on the receptor binding domain displayed on virus-like particles]]** | |
| - | | **888800000013** | **[[https://doi.org/10.1101/2020.04.15.042085|10.1101/2020.04.15.042085]]** | Bestle D (2020) | **[[https://thebiogrid.org/221402/publication|TMPRSS2 and furin are both essential for proteolytic activ | + | | **888800000032** | **[[https://doi.org/10.1101/2020.05.02.043554|10.1101/2020.05.02.043554]]** | Gunther S (2020) | **[[https://thebiogrid.org/221835/publication|Catalytic cleavage of HEAT and subsequent covalent binding of the tetralone moiety by the SARS-CoV-2 main protease]]** | |
| - | ation and spread of SARS-CoV-2 in human airway epithelial cells and provide promising drug targets]]** | | + | | **888800000034** | **[[https://doi.org/10.1101/2020.05.03.074914|10.1101/2020.05.03.074914]]** | Liu X (2020) | **[[https://thebiogrid.org/221959/publication|Neutralizing Antibodies Isolated by a site-directed Screening have Potent Protection on SARS-CoV-2 Infection]]** | |
| - | | **888800000016** | **[[https://doi.org/10.1101/2020.04.14.042010|10.1101/2020.04.14.042010]]** | Chi X (2020) | **[[https://thebiogrid.org/221405/publication|Humanized Single Domain Antibodies Neutralize SARS-CoV-2 by T | + | | **888800000035** | **[[https://doi.org/10.1101/2020.05.21.109157|10.1101/2020.05.21.109157]]** | Lui I (2020) | **[[https://thebiogrid.org/222215/publication|Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with limited intra-Spike avidity]]** | |
| - | argeting Spike Receptor Binding Domain]]** | | + | | **888800000036** | **[[https://doi.org/10.1101/2020.05.21.107870|10.1101/2020.05.21.107870]]** | Partridge LJ (2020) | **[[https://thebiogrid.org/222216/publication|Unfractionated heparin potently inhibits the binding of SARS-CoV-2 spike protein to a human cell line]]** | |
| - | | **888800000018** | **[[https://doi.org/10.1101/2020.04.19.049643|10.1101/2020.04.19.049643]]** | Zeng X (2020) | **[[https://thebiogrid.org/221566/publication|Blocking antibodies against SARS-CoV-2 RBD isolated from a p | + | | **888800000037** | **[[https://doi.org/10.1101/2020.05.13.092478|10.1101/2020.05.13.092478]]** | Chiodo F (2020) | **[[https://thebiogrid.org/222217/publication|Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 Spike Protein to Host Lectins and Lung Microbiota]]** | |
| - | hage display antibody library using a competitive biopanning strategy]]** | | + | | **888800000038** | **[[https://doi.org/10.1101/2020.05.12.091298|10.1101/2020.05.12.091298]]** | Seydoux E (2020) | **[[https://thebiogrid.org/222218/publication|Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual]]** | |
| - | | **888800000019** | **[[https://doi.org/10.1101/2020.04.23.057265|10.1101/2020.04.23.057265]]** | Peng Q (2020) | **[[https://thebiogrid.org/221567/publication|Structural and biochemical characterization of nsp12-nsp7-ns | + | | **888800000039** | **[[https://doi.org/10.1101/2020.05.21.107565|10.1101/2020.05.21.107565]]** | Zang J (2020) | **[[https://thebiogrid.org/222219/publication|Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement]]** | |
| - | p8 core polymerase complex from COVID-19 virus]]** | | + | | **888800000040** | **[[https://doi.org/10.1101/2020.05.12.092171|10.1101/2020.05.12.092171]]** | Zhou X (2020) | **[[https://thebiogrid.org/222220/publication|Structure of SARS-CoV-2 main protease in the apo state reveals the inactive conformation]]** | |
| - | | **888800000020** | **[[https://doi.org/10.1101/2020.04.22.046565|10.1101/2020.04.22.046565]]** | Liu Y (2020) | **[[https://thebiogrid.org/221568/publication|Functional and Genetic Analysis of Viral Receptor ACE2 Orthol | + | | **888800000041** | **[[https://doi.org/10.1101/2020.06.17.156455|10.1101/2020.06.17.156455]]** | Stukalov A (2020) | **[[https://thebiogrid.org/222410/publication|Multi-level proteomics reveals host-perturbation strategies of SARS-CoV-2 and SARS-CoV]]** | |
| - | ogs Reveals Broad Potential Host Range of SARS-CoV-2]]** | | + | | **888800000042** | **[[https://doi.org/10.1101/2020.06.05.135921|10.1101/2020.06.05.135921]]** | Bertoglio F (2020) | **[[https://thebiogrid.org/222602/publication|SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface]]** | |
| - | | **888800000021** | **[[https://doi.org/10.1101/2020.04.21.053017|10.1101/2020.04.21.053017]]** | Walker A (2020) | **[[https://thebiogrid.org/221569/publication|Enisamium is a small molecule inhibitor of the influenza A | + | | **888800000043** | **[[https://doi.org/10.1101/2020.06.05.135699|10.1101/2020.06.05.135699]]** | Moustaqil M (2020) | **[[https://thebiogrid.org/222603/publication|SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts.]]** | |
| - | virus and SARS-CoV-2 RNA polymerases]]** | | + | |
| - | | **888800000022** | **[[https://doi.org/10.1101/2020.04.17.047498|10.1101/2020.04.17.047498]]** | Rosas Lemus M (2020) | **[[https://thebiogrid.org/221570/publication|The crystal structure of nsp10-nsp16 heterodimer from | + | |
| - | SARS CoV-2in complex with S-adenosylmethionine]]** | | + | |
| - | | **888800000025** | **[[https://doi.org/10.1101/2020.04.29.068890|10.1101/2020.04.29.068890]]** | Rut W (2020) | **[[https://thebiogrid.org/221777/publication|Activity profiling of SARS-CoV-2-PLpro protease provides stru | + | |
| - | ctural framework for anti-COVID-19 drug design]]** | | + | |
| - | | **888800000029** | **[[https://doi.org/10.1101/2020.05.02.20086876|10.1101/2020.05.02.20086876]]** | Zhang D (2020) | **[[https://thebiogrid.org/221831/publication|Ultra-fast and onsite interrogation of Severe Acute Res | + | |
| - | piratory Syndrome Coronavirus 2 (SARS-CoV-2) in environmental specimens via surface enhanced Raman scattering (SERS)]]** | | + | |
| - | | **888800000031** | **[[https://doi.org/10.1101/2020.05.06.079830|10.1101/2020.05.06.079830]]** | Zha L (2020) | **[[https://thebiogrid.org/221833/publication|Development of a COVID-19 vaccine based on the receptor bindi | + | |
| - | ng domain displayed on virus-like particles]]** | | + | |
| - | | **888800000032** | **[[https://doi.org/10.1101/2020.05.02.043554|10.1101/2020.05.02.043554]]** | Gunther S (2020) | **[[https://thebiogrid.org/221835/publication|Catalytic cleavage of HEAT and subsequent covalent bindin | + | |
| - | g of the tetralone moiety by the SARS-CoV-2 main protease]]** | | + | |
| - | | **888800000034** | **[[https://doi.org/10.1101/2020.05.03.074914|10.1101/2020.05.03.074914]]** | Liu X (2020) | **[[https://thebiogrid.org/221959/publication|Neutralizing Antibodies Isolated by a site-directed Screening | + | |
| - | have Potent Protection on SARS-CoV-2 Infection]]** | | + | |
| - | | **888800000035** | **[[https://doi.org/10.1101/2020.05.21.109157|10.1101/2020.05.21.109157]]** | Lui I (2020) | **[[https://thebiogrid.org/222215/publication|Trimeric SARS-CoV-2 Spike interacts with dimeric ACE2 with li | + | |
| - | mited intra-Spike avidity]]** | | + | |
| - | | **888800000036** | **[[https://doi.org/10.1101/2020.05.21.107870|10.1101/2020.05.21.107870]]** | Partridge LJ (2020) | **[[https://thebiogrid.org/222216/publication|Unfractionated heparin potently inhibits the binding o | + | |
| - | f SARS-CoV-2 spike protein to a human cell line]]** | | + | |
| - | | **888800000037** | **[[https://doi.org/10.1101/2020.05.13.092478|10.1101/2020.05.13.092478]]** | Chiodo F (2020) | **[[https://thebiogrid.org/222217/publication|Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 | + | |
| - | Spike Protein to Host Lectins and Lung Microbiota]]** | | + | |
| - | | **888800000037** | **[[https://doi.org/10.1101/2020.05.13.092478|10.1101/2020.05.13.092478]]** | Chiodo F (2020) | **[[https://thebiogrid.org/222217/publication|Novel ACE2-Independent Carbohydrate-Binding of SARS-CoV-2 | + | |
| - | Spike Protein to Host Lectins and Lung Microbiota]]** | | + | |
| - | | **888800000038** | **[[https://doi.org/10.1101/2020.05.12.091298|10.1101/2020.05.12.091298]]** | Seydoux E (2020) | **[[https://thebiogrid.org/222218/publication|Characterization of neutralizing antibodies from a SARS-C | + | |
| - | oV-2 infected individual]]** | | + | |
| - | | **888800000039** | **[[https://doi.org/10.1101/2020.05.21.107565|10.1101/2020.05.21.107565]]** | Zang J (2020) | **[[https://thebiogrid.org/222219/publication|Immunization with the receptor-binding domain of SARS-CoV-2 | + | |
| - | elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement]]** | | + | |
| - | | **888800000040** | **[[https://doi.org/10.1101/2020.05.12.092171|10.1101/2020.05.12.092171]]** | Zhou X (2020) | **[[https://thebiogrid.org/222220/publication|Structure of SARS-CoV-2 main protease in the apo state revea | + | |
| - | ls the inactive conformation]]** | | + | |
| - | | **888800000041** | **[[https://doi.org/10.1101/2020.06.17.156455|10.1101/2020.06.17.156455]]** | Stukalov A (2020) | **[[https://thebiogrid.org/222410/publication|Multi-level proteomics reveals host-perturbation strateg | + | |
| - | ies of SARS-CoV-2 and SARS-CoV]]** | | + | |
| - | | **888800000042** | **[[https://doi.org/10.1101/2020.06.05.135921|10.1101/2020.06.05.135921]]** | Bertoglio F (2020) | **[[https://thebiogrid.org/222602/publication|SARS-CoV-2 neutralizing human recombinant antibodies se | + | |
| - | lected from pre-pandemic healthy donors binding at RBD-ACE2 interface]]** | | + | |
| - | | **888800000043** | **[[https://doi.org/10.1101/2020.06.05.135699|10.1101/2020.06.05.135699]]** | Moustaqil M (2020) | **[[https://thebiogrid.org/222603/publication|SARS-CoV-2 proteases cleave IRF3 and critical modulator | + | |
| - | s of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts.]]** | | + | |
| | **888800000045** | **[[https://doi.org/10.1101/2020.06.05.134114|10.1101/2020.06.05.134114]]** | Daly JL (2020) | **[[https://thebiogrid.org/222653/publication|Neuropilin-1 is a host factor for SARS-CoV-2 infection]]** | | | **888800000045** | **[[https://doi.org/10.1101/2020.06.05.134114|10.1101/2020.06.05.134114]]** | Daly JL (2020) | **[[https://thebiogrid.org/222653/publication|Neuropilin-1 is a host factor for SARS-CoV-2 infection]]** | | ||
| - | | **888800000046** | **[[https://doi.org/10.1101/2020.06.17.158121|10.1101/2020.06.17.158121]]** | Cubuk J (2020) | **[[https://thebiogrid.org/222654/publication|The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, | + | | **888800000046** | **[[https://doi.org/10.1101/2020.06.17.158121|10.1101/2020.06.17.158121]]** | Cubuk J (2020) | **[[https://thebiogrid.org/222654/publication|The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA]]** | |
| - | and phase separates with RNA]]** | | + | | **888800000048** | **[[https://doi.org/10.1101/2020.06.02.130161|10.1101/2020.06.02.130161]]** | Hanke L (2020) | **[[https://thebiogrid.org/222656/publication|An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction]]** | |
| - | | **888800000048** | **[[https://doi.org/10.1101/2020.06.02.130161|10.1101/2020.06.02.130161]]** | Hanke L (2020) | **[[https://thebiogrid.org/222656/publication|An alpaca nanobody neutralizes SARS-CoV-2 by blocking recep | + | | **888800000049** | **[[https://doi.org/10.1101/2020.06.17.156471|10.1101/2020.06.17.156471]]** | Conceicao C (2020) | **[[https://thebiogrid.org/222704/publication|The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins]]** | |
| - | tor interaction]]** | | + | | **888800000050** | **[[https://doi.org/10.1101/2020.06.07.138677|10.1101/2020.06.07.138677]]** | Luan X (2020) | **[[https://thebiogrid.org/222705/publication|Structure Basis for Inhibition of SARS-CoV-2 by the Feline Drug GC376]]** | |
| - | | **888800000049** | **[[https://doi.org/10.1101/2020.06.17.156471|10.1101/2020.06.17.156471]]** | Conceicao C (2020) | **[[https://thebiogrid.org/222704/publication|The SARS-CoV-2 Spike protein has a broad tropism for ma | + | | **888800000051** | **[[https://doi.org/10.1101/2020.06.02.129098|10.1101/2020.06.02.129098]]** | Lv Z (2020) | **[[https://thebiogrid.org/222706/publication|Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody]]** | |
| - | mmalian ACE2 proteins]]** | | + | | **888800000052** | **[[https://doi.org/10.1101/2020.06.06.137513|10.1101/2020.06.06.137513]]** | Lou Y (2020) | **[[https://thebiogrid.org/222707/publication|Cross-neutralization antibodies against SARS-CoV-2 and RBD mutations from convalescent patient antibody libraries]]** | |
| - | | **888800000050** | **[[https://doi.org/10.1101/2020.06.07.138677|10.1101/2020.06.07.138677]]** | Luan X (2020) | **[[https://thebiogrid.org/222705/publication|Structure Basis for Inhibition of SARS-CoV-2 by the Feline D | + | | **888800000054** | **[[https://doi.org/10.1101/2020.06.16.155812|10.1101/2020.06.16.155812]]** | Li J (2020) | **[[https://thebiogrid.org/222709/publication|Crystal structure of SARS-CoV-2 main protease in complex with a Chinese herb inhibitor shikonin]]** | |
| - | rug GC376]]** | | + | | **888800000056** | **[[https://doi.org/10.1101/2020.06.16.154708|10.1101/2020.06.16.154708]]** | Hanson QM (2020) | **[[https://thebiogrid.org/223039/publication|Targeting ACE2-RBD interaction as a platform for COVID19 therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay]]** | |
| - | | **888800000051** | **[[https://doi.org/10.1101/2020.06.02.129098|10.1101/2020.06.02.129098]]** | Lv Z (2020) | **[[https://thebiogrid.org/222706/publication|Structural basis for neutralization of SARS-CoV-2 and SARS-CoV | + | | **888800000057** | **[[https://doi.org/10.1101/2020.06.09.20127050|10.1101/2020.06.09.20127050]]** | Gniffke EP (2020) | **[[https://thebiogrid.org/223040/publication|Plasma from recovered COVID19 subjects inhibits spike protein binding to ACE2 in a microsphere-based inhibition assay]]** | |
| - | by a potent therapeutic antibody]]** | | + | | **888800000060** | **[[https://doi.org/10.1101/2020.07.01.182659|10.1101/2020.07.01.182659]]** | Lu J (2020) | **[[https://thebiogrid.org/223093/publication|High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity]]** | |
| - | | **888800000052** | **[[https://doi.org/10.1101/2020.06.06.137513|10.1101/2020.06.06.137513]]** | Lou Y (2020) | **[[https://thebiogrid.org/222707/publication|Cross-neutralization antibodies against SARS-CoV-2 and RBD mu | + | | **888800000062** | **[[https://doi.org/10.1101/2020.07.04.187757|10.1101/2020.07.04.187757]]** | Yurkovetskiy L (2020) | **[[https://thebiogrid.org/223095/publication|Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant]]** | |
| - | tations from convalescent patient antibody libraries]]** | | + | | **888800000063** | **[[https://doi.org/10.1101/2020.07.31.230730|10.1101/2020.07.31.230730]]** | Cao W (2020) | **[[https://thebiogrid.org/223096/publication|Biomechanical Characterization of SARS-CoV-2 Spike RBD and Human ACE2 Protein-Protein Interaction]]** | |
| - | | **888800000054** | **[[https://doi.org/10.1101/2020.06.16.155812|10.1101/2020.06.16.155812]]** | Li J (2020) | **[[https://thebiogrid.org/222709/publication|Crystal structure of SARS-CoV-2 main protease in complex with | + | | **888800000064** | **[[https://doi.org/10.1101/2020.07.24.219857|10.1101/2020.07.24.219857]]** | Esparza TJ (2020) | **[[https://thebiogrid.org/223097/publication|High Affinity Nanobodies Block SARS-CoV-2 Spike Receptor Binding Domain Interaction with Human Angiotensin Converting Enzyme]]** | |
| - | a Chinese herb inhibitor shikonin]]** | | + | | **888800000065** | **[[https://doi.org/10.1101/2020.07.25.221036|10.1101/2020.07.25.221036]]** | Shilts J (2020) | **[[https://thebiogrid.org/223098/publication|No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor]]** | |
| - | | **888800000056** | **[[https://doi.org/10.1101/2020.06.16.154708|10.1101/2020.06.16.154708]]** | Hanson QM (2020) | **[[https://thebiogrid.org/223039/publication|Targeting ACE2-RBD interaction as a platform for COVID19 | + | | **888800000066** | **[[https://doi.org/10.1101/2020.07.13.201517|10.1101/2020.07.13.201517]]** | Davies JP (2020) | **[[https://thebiogrid.org/223099/publication|Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies]]** | |
| - | therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay]]** | | + | | **888800000067** | **[[https://doi.org/10.1101/2020.07.31.229781|10.1101/2020.07.31.229781]]** | Alitongbieke G (2020) | **[[https://thebiogrid.org/223100/publication|Study on beta-Chitosan against the binding of SARS-CoV-2S-RBD/ACE2]]** | |
| - | | **888800000057** | **[[https://doi.org/10.1101/2020.06.09.20127050|10.1101/2020.06.09.20127050]]** | Gniffke EP (2020) | **[[https://thebiogrid.org/223040/publication|Plasma from recovered COVID19 subjects inhibits spik | + | | **888800000068** | **[[https://doi.org/10.1101/2020.07.31.231746|10.1101/2020.07.31.231746]]** | Glasgow A (2020) | **[[https://thebiogrid.org/223101/publication|Engineered ACE2 receptor traps potently neutralize SARS-CoV-2]]** | |
| - | e protein binding to ACE2 in a microsphere-based inhibition assay]]** | | + | | **888800000069** | **[[https://doi.org/10.1101/2020.07.27.224089|10.1101/2020.07.27.224089]]** | Beasley MD (2020) | **[[https://thebiogrid.org/223102/publication|Antibodies that potently inhibit or enhance SARS-CoV-2 spike protein-ACE2 interaction isolated from synthetic single-chain antibody libraries]]** | |
| - | | **888800000060** | **[[https://doi.org/10.1101/2020.07.01.182659|10.1101/2020.07.01.182659]]** | Lu J (2020) | **[[https://thebiogrid.org/223093/publication|High affinity binding of SARS-CoV-2 spike protein enhances ACE | + | | **888800000070** | **[[https://doi.org/10.1101/2020.07.29.227462|10.1101/2020.07.29.227462]]** | Gao C (2020) | **[[https://thebiogrid.org/223103/publication|SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors]]** | |
| - | 2 carboxypeptidase activity]]** | | + | | **888800000071** | **[[https://doi.org/10.1101/2020.07.26.222026|10.1101/2020.07.26.222026]]** | Zheng Y (2020) | **[[https://thebiogrid.org/223104/publication|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling]]** | |
| - | | **888800000062** | **[[https://doi.org/10.1101/2020.07.04.187757|10.1101/2020.07.04.187757]]** | Yurkovetskiy L (2020) | **[[https://thebiogrid.org/223095/publication|Structural and Functional Analysis of the D614G SARS | + | | **888800000072** | **[[https://doi.org/10.1101/2020.07.30.229187|10.1101/2020.07.30.229187]]** | Shi W (2020) | **[[https://thebiogrid.org/223105/publication|A dynamic regulatory interface on SARS-CoV-2 RNA polymerase]]** | |
| - | -CoV-2 Spike Protein Variant]]** | | + | | **888800000075** | **[[https://doi.org/10.1101/2020.07.15.204404|10.1101/2020.07.15.204404]]** | Schmidt N (2020) | **[[https://thebiogrid.org/223108/publication|A direct RNA-protein interaction atlas of the SARS-CoV-2 RNA in infected human cells]]** | |
| - | | **888800000063** | **[[https://doi.org/10.1101/2020.07.31.230730|10.1101/2020.07.31.230730]]** | Cao W (2020) | **[[https://thebiogrid.org/223096/publication|Biomechanical Characterization of SARS-CoV-2 Spike RBD and Hu | + | | **888800000076** | **[[https://doi.org/10.1101/2020.08.03.234914|10.1101/2020.08.03.234914]]** | Cao L (2020) | **[[https://thebiogrid.org/223109/publication|De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. [DEPRECATED]]]** | |
| - | man ACE2 Protein-Protein Interaction]]** | | + | | **888800000077** | **[[https://doi.org/10.1101/2020.07.27.223727|10.1101/2020.07.27.223727]]** | Sacco MD (2020) | **[[https://thebiogrid.org/223110/publication|Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against Mpro and cathepsin L]]** | |
| - | | **888800000064** | **[[https://doi.org/10.1101/2020.07.24.219857|10.1101/2020.07.24.219857]]** | Esparza TJ (2020) | **[[https://thebiogrid.org/223097/publication|High Affinity Nanobodies Block SARS-CoV-2 Spike Receptor | + | | **888800000078** | **[[https://doi.org/10.1101/2020.07.17.208959|10.1101/2020.07.17.208959]]** | Fu Z (2020) | **[[https://thebiogrid.org/223111/publication|Structural basis for the inhibition of the papain-like protease of SARS-CoV-2 by small molecules]]** | |
| - | Binding Domain Interaction with Human Angiotensin Converting Enzyme]]** | | + | | **888800000079** | **[[https://doi.org/10.1101/2020.07.31.231282|10.1101/2020.07.31.231282]]** | Tee KL (2020) | **[[https://thebiogrid.org/223112/publication|Purification of recombinant SARS-CoV-2 spike, its receptor binding domain, and CR3022 mAb for serological assay]]** | |
| - | | **888800000065** | **[[https://doi.org/10.1101/2020.07.25.221036|10.1101/2020.07.25.221036]]** | Shilts J (2020) | **[[https://thebiogrid.org/223098/publication|No evidence for basigin/CD147 as a direct SARS-CoV-2 spike | + | | **888800000080** | **[[https://doi.org/10.1101/2020.07.25.220806|10.1101/2020.07.25.220806]]** | Temerozo JR (2020) | **[[https://thebiogrid.org/223113/publication|The neuropeptides VIP and PACAP inhibit SARS-CoV-2 replication in monocytes and lung epithelial cells and decrease the production of proinflammatory cytokines in infected cells.]]** | |
| - | binding receptor]]** | | + | | **888800000081** | **[[https://doi.org/10.1101/2020.08.03.234559|10.1101/2020.08.03.234559]]** | Addetia A (2020) | **[[https://thebiogrid.org/223399/publication|SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98]]** | |
| - | | **888800000066** | **[[https://doi.org/10.1101/2020.07.13.201517|10.1101/2020.07.13.201517]]** | Davies JP (2020) | **[[https://thebiogrid.org/223099/publication|Comparative multiplexed interactomics of SARS-CoV-2 and h | + | | **888800000082** | **[[https://doi.org/10.1101/2020.08.28.272955|10.1101/2020.08.28.272955]]** | Laurent E (2020) | **[[https://thebiogrid.org/223400/publication|Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms]]** | |
| - | omologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies]]** | | + | | **888800000083** | **[[https://doi.org/10.1101/2020.08.20.259770|10.1101/2020.08.20.259770]]** | Lapointe CP (2020) | **[[https://thebiogrid.org/223461/publication|Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation]]** | |
| - | | **888800000067** | **[[https://doi.org/10.1101/2020.07.31.229781|10.1101/2020.07.31.229781]]** | Alitongbieke G (2020) | **[[https://thebiogrid.org/223100/publication|Study on beta-Chitosan against the binding of SARS-C | + | | **888800000084** | **[[https://doi.org/10.1101/2020.08.16.252973|10.1101/2020.08.16.252973]]** | Han L (2020) | **[[https://thebiogrid.org/223462/publication|SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Targeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways]]** | |
| - | oV-2S-RBD/ACE2]]** | | + | |
| - | | **888800000068** | **[[https://doi.org/10.1101/2020.07.31.231746|10.1101/2020.07.31.231746]]** | Glasgow A (2020) | **[[https://thebiogrid.org/223101/publication|Engineered ACE2 receptor traps potently neutralize SARS-C | + | |
| - | oV-2]]** | | + | |
| - | | **888800000069** | **[[https://doi.org/10.1101/2020.07.27.224089|10.1101/2020.07.27.224089]]** | Beasley MD (2020) | **[[https://thebiogrid.org/223102/publication|Antibodies that potently inhibit or enhance SARS-CoV-2 s | + | |
| - | pike protein-ACE2 interaction isolated from synthetic single-chain antibody libraries]]** | | + | |
| - | | **888800000070** | **[[https://doi.org/10.1101/2020.07.29.227462|10.1101/2020.07.29.227462]]** | Gao C (2020) | **[[https://thebiogrid.org/223103/publication|SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immun | + | |
| - | e Receptors]]** | | + | |
| - | | **888800000071** | **[[https://doi.org/10.1101/2020.07.26.222026|10.1101/2020.07.26.222026]]** | Zheng Y (2020) | **[[https://thebiogrid.org/223104/publication|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 | + | |
| - | ) Membrane (M) Protein Inhibits Type I and III Interferon Production by Targeting RIG-I/MDA-5 Signaling]]** | | + | |
| - | | **888800000072** | **[[https://doi.org/10.1101/2020.07.30.229187|10.1101/2020.07.30.229187]]** | Shi W (2020) | **[[https://thebiogrid.org/223105/publication|A dynamic regulatory interface on SARS-CoV-2 RNA polymerase]] | + | |
| - | ** | | + | |
| - | | **888800000075** | **[[https://doi.org/10.1101/2020.07.15.204404|10.1101/2020.07.15.204404]]** | Schmidt N (2020) | **[[https://thebiogrid.org/223108/publication|A direct RNA-protein interaction atlas of the SARS-CoV-2 | + | |
| - | RNA in infected human cells]]** | | + | |
| - | | **888800000076** | **[[https://doi.org/10.1101/2020.08.03.234914|10.1101/2020.08.03.234914]]** | Cao L (2020) | **[[https://thebiogrid.org/223109/publication|De novo design of picomolar SARS-CoV-2 miniprotein inhibitors | + | |
| - | . [DEPRECATED]]]** | | + | |
| - | | **888800000077** | **[[https://doi.org/10.1101/2020.07.27.223727|10.1101/2020.07.27.223727]]** | Sacco MD (2020) | **[[https://thebiogrid.org/223110/publication|Structure and inhibition of the SARS-CoV-2 main protease r | + | |
| - | eveals strategy for developing dual inhibitors against Mpro and cathepsin L]]** | | + | |
| - | | **888800000078** | **[[https://doi.org/10.1101/2020.07.17.208959|10.1101/2020.07.17.208959]]** | Fu Z (2020) | **[[https://thebiogrid.org/223111/publication|Structural basis for the inhibition of the papain-like proteas | + | |
| - | e of SARS-CoV-2 by small molecules]]** | | + | |
| - | | **888800000079** | **[[https://doi.org/10.1101/2020.07.31.231282|10.1101/2020.07.31.231282]]** | Tee KL (2020) | **[[https://thebiogrid.org/223112/publication|Purification of recombinant SARS-CoV-2 spike, its receptor b | + | |
| - | inding domain, and CR3022 mAb for serological assay]]** | | + | |
| - | | **888800000080** | **[[https://doi.org/10.1101/2020.07.25.220806|10.1101/2020.07.25.220806]]** | Temerozo JR (2020) | **[[https://thebiogrid.org/223113/publication|The neuropeptides VIP and PACAP inhibit SARS-CoV-2 repl | + | |
| - | ication in monocytes and lung epithelial cells and decrease the production of proinflammatory cytokines in infected cells.]]** | | + | |
| - | | **888800000081** | **[[https://doi.org/10.1101/2020.08.03.234559|10.1101/2020.08.03.234559]]** | Addetia A (2020) | **[[https://thebiogrid.org/223399/publication|SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport thro | + | |
| - | ugh interactions with Rae1 and Nup98]]** | | + | |
| - | | **888800000082** | **[[https://doi.org/10.1101/2020.08.28.272955|10.1101/2020.08.28.272955]]** | Laurent E (2020) | **[[https://thebiogrid.org/223400/publication|Global BioID-based SARS-CoV-2 proteins proximal interacto | + | |
| - | me unveils novel ties between viral polypeptides and host factors involved in multiple COVID19-associated mechanisms]]** | | + | |
| - | | **888800000083** | **[[https://doi.org/10.1101/2020.08.20.259770|10.1101/2020.08.20.259770]]** | Lapointe CP (2020) | **[[https://thebiogrid.org/223461/publication|Dynamic competition between SARS-CoV-2 NSP1 and mRNA on | + | |
| - | the human ribosome inhibits translation initiation]]** | | + | |
| - | | **888800000084** | **[[https://doi.org/10.1101/2020.08.16.252973|10.1101/2020.08.16.252973]]** | Han L (2020) | **[[https://thebiogrid.org/223462/publication|SARS-CoV-2 ORF9b Antagonizes Type I and III Interferons by Ta | + | |
| - | rgeting Multiple Components of RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING Signaling Pathways]]** | | + | |
| | **888800000085** | **[[https://doi.org/10.1101/2020.08.06.238915|10.1101/2020.08.06.238915]]** | Watson A (2020) | **[[https://thebiogrid.org/223463/publication|Peptide Antidotes to SARS-CoV-2 (COVID-19)]]** | | | **888800000085** | **[[https://doi.org/10.1101/2020.08.06.238915|10.1101/2020.08.06.238915]]** | Watson A (2020) | **[[https://thebiogrid.org/223463/publication|Peptide Antidotes to SARS-CoV-2 (COVID-19)]]** | | ||
| - | | **888800000086** | **[[https://doi.org/10.1101/2020.08.12.247767|10.1101/2020.08.12.247767]]** | Yang Z (2020) | **[[https://thebiogrid.org/223464/publication|Suppression of MDA5-mediated antiviral immune responses by N | + | | **888800000086** | **[[https://doi.org/10.1101/2020.08.12.247767|10.1101/2020.08.12.247767]]** | Yang Z (2020) | **[[https://thebiogrid.org/223464/publication|Suppression of MDA5-mediated antiviral immune responses by NSP8 of SARS-CoV-2]]** | |
| - | SP8 of SARS-CoV-2]]** | | + | | **888800000087** | **[[https://doi.org/10.1101/2020.08.12.246389|10.1101/2020.08.12.246389]]** | Risner K (2020) | **[[https://thebiogrid.org/223465/publication|Maraviroc inhibits SARS-CoV-2 multiplication and s-protein mediated cell fusion in cell culture]]** | |
| - | | **888800000087** | **[[https://doi.org/10.1101/2020.08.12.246389|10.1101/2020.08.12.246389]]** | Risner K (2020) | **[[https://thebiogrid.org/223465/publication|Maraviroc inhibits SARS-CoV-2 multiplication and s-protein | + | | **888800000088** | **[[https://doi.org/10.1101/2020.08.08.238469|10.1101/2020.08.08.238469]]** | Schoof M (2020) | **[[https://thebiogrid.org/223466/publication|An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation]]** | |
| - | mediated cell fusion in cell culture]]** | | + | | **888800000089** | **[[https://doi.org/10.1101/2020.08.14.250258|10.1101/2020.08.14.250258]]** | Chen Y (2020) | **[[https://thebiogrid.org/223467/publication|Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro]]** | |
| - | | **888800000088** | **[[https://doi.org/10.1101/2020.08.08.238469|10.1101/2020.08.08.238469]]** | Schoof M (2020) | **[[https://thebiogrid.org/223466/publication|An ultra-high affinity synthetic nanobody blocks SARS-CoV- | + | | **888800000090** | **[[https://doi.org/10.1101/2020.08.09.242917|10.1101/2020.08.09.242917]]** | Thepaut M (2020) | **[[https://thebiogrid.org/223468/publication|DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist]]** | |
| - | 2 infection by locking Spike into an inactive conformation]]** | | + | | **888800000091** | **[[https://doi.org/10.1101/2020.08.07.241877|10.1101/2020.08.07.241877]]** | Hassert M (2020) | **[[https://thebiogrid.org/223469/publication|mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2]]** | |
| - | | **888800000089** | **[[https://doi.org/10.1101/2020.08.14.250258|10.1101/2020.08.14.250258]]** | Chen Y (2020) | **[[https://thebiogrid.org/223467/publication|Inhibition of Severe Acute Respiratory Syndrome Coronavirus | + | | **888800000092** | **[[https://doi.org/10.1101/2020.08.09.243451|10.1101/2020.08.09.243451]]** | Yuan S (2020) | **[[https://thebiogrid.org/223470/publication|Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA.]]** | |
| - | 2 main protease by tafenoquine in vitro]]** | | + | | **888800000093** | **[[https://doi.org/10.1101/2020.08.18.256776|10.1101/2020.08.18.256776]]** | Andres AD (2020) | **[[https://thebiogrid.org/223471/publication|SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells]]** | |
| - | | **888800000090** | **[[https://doi.org/10.1101/2020.08.09.242917|10.1101/2020.08.09.242917]]** | Thepaut M (2020) | **[[https://thebiogrid.org/223468/publication|DC/L-SIGN recognition of spike glycoprotein promotes SARS | + | | **888800000094** | **[[https://doi.org/10.1101/2020.08.13.249177|10.1101/2020.08.13.249177]]** | Carrique L (2020) | **[[https://thebiogrid.org/223473/publication|The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer]]** | |
| - | -CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist]]** | | + | | **888800000095** | **[[https://doi.org/10.1101/2020.08.13.248211|10.1101/2020.08.13.248211]]** | Baddock HT (2020) | **[[https://thebiogrid.org/223474/publication|Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification]]** | |
| - | | **888800000091** | **[[https://doi.org/10.1101/2020.08.07.241877|10.1101/2020.08.07.241877]]** | Hassert M (2020) | **[[https://thebiogrid.org/223469/publication|mRNA induced expression of human angiotensin-converting e | + | | **888800000096** | **[[https://doi.org/10.1101/2020.08.10.244525|10.1101/2020.08.10.244525]]** | Malla TN (2020) | **[[https://thebiogrid.org/223475/publication|Ebselen Reacts with SARS Coronavirus-2 Main Protease Crystals]]** | |
| - | nzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2]]** | | + | | **888800000097** | **[[https://doi.org/10.1101/2020.08.11.244863|10.1101/2020.08.11.244863]]** | Pillon MC (2020) | **[[https://thebiogrid.org/223476/publication|Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15]]** | |
| - | | **888800000092** | **[[https://doi.org/10.1101/2020.08.09.243451|10.1101/2020.08.09.243451]]** | Yuan S (2020) | **[[https://thebiogrid.org/223470/publication|Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenic | + | | **888800000098** | **[[https://doi.org/10.1101/2020.08.12.247338|10.1101/2020.08.12.247338]]** | Wang C (2020) | **[[https://thebiogrid.org/223477/publication|Membrane Nanoparticles Derived from ACE2-rich Cells Block SARS-CoV-2 Infection]]** | |
| - | ity factor redirecting host protein synthesis machinery toward viral RNA.]]** | | + | | **888800000099** | **[[https://doi.org/10.1101/2020.08.14.251421|10.1101/2020.08.14.251421]]** | Wilamowski M (2020) | **[[https://thebiogrid.org/223478/publication|Methylation of RNA Cap in SARS-CoV-2 captured by serial crystallography]]** | |
| - | | **888800000093** | **[[https://doi.org/10.1101/2020.08.18.256776|10.1101/2020.08.18.256776]]** | Andres AD (2020) | **[[https://thebiogrid.org/223471/publication|SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Su | + | | **888800000100** | **[[https://doi.org/10.1101/2020.08.13.248872|10.1101/2020.08.13.248872]]** | Wei C (2020) | **[[https://thebiogrid.org/223479/publication|SARS-CoV-2 manipulates the SR-B1-mediated HDL uptake pathway for its entry]]** | |
| - | ppresses Antiviral Responses in Cells]]** | | + | | **888800000101** | **[[https://doi.org/10.1101/2020.08.14.251207|10.1101/2020.08.14.251207]]** | Heaton BE (2020) | **[[https://thebiogrid.org/223480/publication|SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2]]** | |
| - | | **888800000094** | **[[https://doi.org/10.1101/2020.08.13.249177|10.1101/2020.08.13.249177]]** | Carrique L (2020) | **[[https://thebiogrid.org/223473/publication|The SARS-CoV-2 Spike harbours a lipid binding pocket whi | + | | **888800000102** | **[[https://doi.org/10.1101/2020.08.07.20169441|10.1101/2020.08.07.20169441]]** | Johari YB (2020) | **[[https://thebiogrid.org/223481/publication|Production of Trimeric SARS-CoV-2 Spike Protein by CHO Cells for Serological COVID-19 Testing]]** | |
| - | ch modulates stability of the prefusion trimer]]** | | + | | **888800000103** | **[[https://doi.org/10.1101/2020.08.09.242867|10.1101/2020.08.09.242867]]** | Gai J (2020) | **[[https://thebiogrid.org/223482/publication|A potent neutralizing nanobody against SARS-CoV-2 with inhaled delivery potential]]** | |
| - | | **888800000095** | **[[https://doi.org/10.1101/2020.08.13.248211|10.1101/2020.08.13.248211]]** | Baddock HT (2020) | **[[https://thebiogrid.org/223474/publication|Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10 | + | | **888800000104** | **[[https://doi.org/10.1101/2020.09.03.282103|10.1101/2020.09.03.282103]]** | Samavarchi-Tehrani P (2020) | **[[https://thebiogrid.org/223517/publication|A SARS-CoV-2 - host proximity interactome]]** | |
| - | ) complex: implications for its role in viral genome stability and inhibitor identification]]** | | + | | **888800000105** | **[[https://doi.org/10.1101/2020.09.09.287508|10.1101/2020.09.09.287508]]** | Gu Y (2020) | **[[https://thebiogrid.org/223561/publication|Interaction network of SARS-CoV-2 with host receptome through spike protein]]** | |
| - | | **888800000096** | **[[https://doi.org/10.1101/2020.08.10.244525|10.1101/2020.08.10.244525]]** | Malla TN (2020) | **[[https://thebiogrid.org/223475/publication|Ebselen Reacts with SARS Coronavirus-2 Main Protease Cryst | + | | **888800000106** | **[[https://doi.org/10.1101/2020.08.29.273441|10.1101/2020.08.29.273441]]** | Bojadzic D (2020) | **[[https://thebiogrid.org/223562/publication|Methylene Blue Inhibits In Vitro the SARS-CoV-2 Spike - ACE2 Protein-Protein Interaction - A Mechanism That Can Contribute to Its Antiviral Activity Against COVID-19]]** | |
| - | als]]** | | + | | **888800000107** | **[[https://doi.org/10.1101/2020.09.04.282558|10.1101/2020.09.04.282558]]** | Bouwman KM (2020) | **[[https://thebiogrid.org/223563/publication|Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins]]** | |
| - | | **888800000097** | **[[https://doi.org/10.1101/2020.08.11.244863|10.1101/2020.08.11.244863]]** | Pillon MC (2020) | **[[https://thebiogrid.org/223476/publication|Cryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp | + | | **888800000108** | **[[https://doi.org/10.1101/2020.08.28.271601|10.1101/2020.08.28.271601]]** | Dash P (2020) | **[[https://thebiogrid.org/223564/publication|Sequence analysis of Indian SARS-CoV-2 isolates shows a stronger interaction of mutated receptor binding domain with ACE2 receptor]]** | |
| - | 15]]** | | + | | **888800000109** | **[[https://doi.org/10.1101/2020.08.28.269175|10.1101/2020.08.28.269175]]** | St-Germain JR (2020) | **[[https://thebiogrid.org/223565/publication|A SARS-CoV-2 BioID-based virus-host membrane protein interactome and virus peptide compendium: new proteomics resources for COVID-19 research]]** | |
| - | | **888800000098** | **[[https://doi.org/10.1101/2020.08.12.247338|10.1101/2020.08.12.247338]]** | Wang C (2020) | **[[https://thebiogrid.org/223477/publication|Membrane Nanoparticles Derived from ACE2-rich Cells Block SA | + | | **888800000111** | **[[https://doi.org/10.1101/2020.09.04.280081|10.1101/2020.09.04.280081]]** | Qiang X (2020) | **[[https://thebiogrid.org/223567/publication|Monoclonal Antibodies Capable of Binding SARS-CoV-2 Spike Protein Receptor Binding Motif Specifically Prevent GM-CSF Induction.]]** | |
| - | RS-CoV-2 Infection]]** | | + | | **888800000112** | **[[https://doi.org/10.1101/2020.09.09.287987|10.1101/2020.09.09.287987]]** | Durdagi S (2020) | **[[https://thebiogrid.org/223568/publication|Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing]]** | |
| - | | **888800000099** | **[[https://doi.org/10.1101/2020.08.14.251421|10.1101/2020.08.14.251421]]** | Wilamowski M (2020) | **[[https://thebiogrid.org/223478/publication|Methylation of RNA Cap in SARS-CoV-2 captured by seria | + | | **888800000113** | **[[https://doi.org/10.1101/2020.09.01.277954|10.1101/2020.09.01.277954]]** | Bartolome A (2020) | **[[https://thebiogrid.org/223569/publication|Angiotensin converting enzyme 2 is a novel target of the secretase complex]]** | |
| - | l crystallography]]** | | + | | **888800000114** | **[[https://doi.org/10.1101/2020.08.31.274704|10.1101/2020.08.31.274704]]** | Guo L (2020) | **[[https://thebiogrid.org/223570/publication|Engineered Trimeric ACE2 Binds and Locks "Three-up" Spike Protein to Potently Inhibit SARS-CoVs and Mutants]]** | |
| - | | **888800000100** | **[[https://doi.org/10.1101/2020.08.13.248872|10.1101/2020.08.13.248872]]** | Wei C (2020) | **[[https://thebiogrid.org/223479/publication|SARS-CoV-2 manipulates the SR-B1-mediated HDL uptake pathway | + | | **888800000115** | **[[https://doi.org/10.1101/2020.09.09.289488|10.1101/2020.09.09.289488]]** | Kotani N (2020) | **[[https://thebiogrid.org/223571/publication|Candidate screening of host cell membrane proteins involved in SARS-CoV-2 entry]]** | |
| - | for its entry]]** | | + | | **888800000116** | **[[https://doi.org/10.1101/2020.08.27.270637|10.1101/2020.08.27.270637]]** | Flower TG (2020) | **[[https://thebiogrid.org/223572/publication|Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion]]** | |
| - | | **888800000101** | **[[https://doi.org/10.1101/2020.08.14.251207|10.1101/2020.08.14.251207]]** | Heaton BE (2020) | **[[https://thebiogrid.org/223480/publication|SRSF protein kinases 1 and 2 are essential host factors f | + | | **888800000117** | **[[https://doi.org/10.1101/2020.09.21.307439|10.1101/2020.09.21.307439]]** | Wang X (2020) | **[[https://thebiogrid.org/223769/publication|Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution]]** | |
| - | or human coronaviruses including SARS-CoV-2]]** | | + | | **888800000118** | **[[https://doi.org/10.1101/2020.09.14.295956|10.1101/2020.09.14.295956]]** | Lin C (2020) | **[[https://thebiogrid.org/223770/publication|Ceftazidime Is a Potential Drug to Inhibit SARS-CoV-2 Infection In Vitro by Blocking Spike Protein-ACE2 Interaction]]** | |
| - | | **888800000102** | **[[https://doi.org/10.1101/2020.08.07.20169441|10.1101/2020.08.07.20169441]]** | Johari YB (2020) | **[[https://thebiogrid.org/223481/publication|Production of Trimeric SARS-CoV-2 Spike Protein by CH | + | | **888800000119** | **[[https://doi.org/10.1101/2020.09.16.297366|10.1101/2020.09.16.297366]]** | Sagar S (2020) | **[[https://thebiogrid.org/223771/publication|Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells]]** | |
| - | O Cells for Serological COVID-19 Testing]]** | | + | | **888800000120** | **[[https://doi.org/10.1101/2020.09.18.301952|10.1101/2020.09.18.301952]]** | Xiao T (2020) | **[[https://thebiogrid.org/223772/publication|A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitro]]** | |
| - | | **888800000103** | **[[https://doi.org/10.1101/2020.08.09.242867|10.1101/2020.08.09.242867]]** | Gai J (2020) | **[[https://thebiogrid.org/223482/publication|A potent neutralizing nanobody against SARS-CoV-2 with inhale | + | | **888800000121** | **[[https://doi.org/10.1101/2020.09.16.297945|10.1101/2020.09.16.297945]]** | Meyer B (2020) | **[[https://thebiogrid.org/223773/publication|Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing]]** | |
| - | d delivery potential]]** | | + | | **888800000122** | **[[https://doi.org/10.1101/2020.09.22.308338|10.1101/2020.09.22.308338]]** | Wagner TR (2020) | **[[https://thebiogrid.org/223774/publication|NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutralizing immune response]]** | |
| - | | **888800000104** | **[[https://doi.org/10.1101/2020.09.03.282103|10.1101/2020.09.03.282103]]** | Samavarchi-Tehrani P (2020) | **[[https://thebiogrid.org/223517/publication|A SARS-CoV-2 - host proximity interactome]]** | + | | **888800000123** | **[[https://doi.org/10.1101/2020.09.20.297242|10.1101/2020.09.20.297242]]** | Ren W (2020) | **[[https://thebiogrid.org/223775/publication|Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry]]** | |
| - | | | + | | **888800000124** | **[[https://doi.org/10.1101/2020.09.13.295691|10.1101/2020.09.13.295691]]** | Olaleye OA (2020) | **[[https://thebiogrid.org/223776/publication|Ambroxol Hydrochloride Inhibits the Interaction between Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein's Receptor Binding Domain and Recombinant Human ACE2.]]** | |
| - | | **888800000105** | **[[https://doi.org/10.1101/2020.09.09.287508|10.1101/2020.09.09.287508]]** | Gu Y (2020) | **[[https://thebiogrid.org/223561/publication|Interaction network of SARS-CoV-2 with host receptome through | + | | **888800000125** | **[[https://doi.org/10.1101/2020.09.16.300319|10.1101/2020.09.16.300319]]** | Tada T (2020) | **[[https://thebiogrid.org/223777/publication|A soluble ACE2 microbody protein fused to a single immunoglobulin Fc domain is a potent inhibitor of SARS-CoV-2 infection in cell culture]]** | |
| - | spike protein]]** | | + | | **888800000126** | **[[https://doi.org/10.1101/2020.09.16.299891|10.1101/2020.09.16.299891]]** | Higuchi Y (2020) | **[[https://thebiogrid.org/223778/publication|High affinity modified ACE2 receptors prevent SARS-CoV-2 infection]]** | |
| - | | **888800000106** | **[[https://doi.org/10.1101/2020.08.29.273441|10.1101/2020.08.29.273441]]** | Bojadzic D (2020) | **[[https://thebiogrid.org/223562/publication|Methylene Blue Inhibits In Vitro the SARS-CoV-2 Spike - | + | | **888800000127** | **[[https://doi.org/10.1101/2020.09.16.20190694|10.1101/2020.09.16.20190694]]** | Ichimura T (2020) | **[[https://thebiogrid.org/223779/publication|KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and Kidney]]** | |
| - | ACE2 Protein-Protein Interaction - A Mechanism That Can Contribute to Its Antiviral Activity Against COVID-19]]** | | + | | **888800000128** | **[[https://doi.org/10.1101/2020.11.04.361154|10.1101/2020.11.04.361154]]** | de Vries (2020) | **[[https://thebiogrid.org/225841/publication|Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets]]** | |
| - | | **888800000107** | **[[https://doi.org/10.1101/2020.09.04.282558|10.1101/2020.09.04.282558]]** | Bouwman KM (2020) | **[[https://thebiogrid.org/223563/publication|Multimerization- and glycosylation-dependent receptor bi | + | | **888800000129** | **[[https://doi.org/10.1101/2020.10.13.336800|10.1101/2020.10.13.336800]]** | Yan R (2020) | **[[https://thebiogrid.org/225985/publication|Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies]]** | |
| - | nding of SARS-CoV-2 spike proteins]]** | | + | | **888800000130** | **[[https://doi.org/10.1101/2020.09.27.315796|10.1101/2020.09.27.315796]]** | Bauer MS (2020) | **[[https://thebiogrid.org/225986/publication|A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Interaction under Constant Force]]** | |
| - | | **888800000108** | **[[https://doi.org/10.1101/2020.08.28.271601|10.1101/2020.08.28.271601]]** | Dash P (2020) | **[[https://thebiogrid.org/223564/publication|Sequence analysis of Indian SARS-CoV-2 isolates shows a stro | + | | **888800000131** | **[[https://doi.org/10.1101/2020.10.06.328112|10.1101/2020.10.06.328112]]** | Lutomski CA (2020) | **[[https://thebiogrid.org/225987/publication|Autoproteolytic Products of the SARS-CoV-2 Nucleocapsid Protein are Primed for Antibody Evasion and Virus Proliferation]]** | |
| - | nger interaction of mutated receptor binding domain with ACE2 receptor]]** | | + | | **888800000132** | **[[https://doi.org/10.1101/2020.10.31.363473|10.1101/2020.10.31.363473]]** | Stevens BR (2020) | **[[https://thebiogrid.org/225988/publication|TMPRSS2 and ADAM17 interactions with ACE2 complexed with SARS-CoV-2 and B0AT1 putatively in intestine, cardiomyocytes, and kidney]]** | |
| - | | **888800000109** | **[[https://doi.org/10.1101/2020.08.28.269175|10.1101/2020.08.28.269175]]** | St-Germain JR (2020) | **[[https://thebiogrid.org/223565/publication|A SARS-CoV-2 BioID-based virus-host membrane protein | + | | **888800000133** | **[[https://doi.org/10.1101/2020.10.23.350348|10.1101/2020.10.23.350348]]** | Tang X (2020) | **[[https://thebiogrid.org/225989/publication|Transferrin receptor is another receptor for SARS-CoV-2 entry]]** | |
| - | interactome and virus peptide compendium: new proteomics resources for COVID-19 research]]** | | + | | **888800000134** | **[[https://doi.org/10.1101/2020.11.04.361576|10.1101/2020.11.04.361576]]** | Li W (2020) | **[[https://thebiogrid.org/225990/publication|Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network]]** | |
| - | | **888800000111** | **[[https://doi.org/10.1101/2020.09.04.280081|10.1101/2020.09.04.280081]]** | Qiang X (2020) | **[[https://thebiogrid.org/223567/publication|Monoclonal Antibodies Capable of Binding SARS-CoV-2 Spike P | + | | **888800000135** | **[[https://doi.org/10.1101/2020.10.29.352450|10.1101/2020.10.29.352450]]** | Bakovic A (2020) | **[[https://thebiogrid.org/225991/publication|Brilacidin, a COVID-19 Drug Candidate, Exhibits Potent In Vitro Antiviral Activity Against SARS-CoV-2]]** | |
| - | rotein Receptor Binding Motif Specifically Prevent GM-CSF Induction.]]** | | + | | **888800000136** | **[[https://doi.org/10.1101/2020.10.26.356048|10.1101/2020.10.26.356048]]** | Liu G (2020) | **[[https://thebiogrid.org/225992/publication|ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease]]** | |
| - | | **888800000112** | **[[https://doi.org/10.1101/2020.09.09.287987|10.1101/2020.09.09.287987]]** | Durdagi S (2020) | **[[https://thebiogrid.org/223568/publication|Near-Physiological-Temperature Serial Femtosecond X-ray C | + | | **888800000137** | **[[https://doi.org/10.1101/2020.10.16.342097|10.1101/2020.10.16.342097]]** | Gao X (2020) | **[[https://thebiogrid.org/225993/publication|Duple extinguishment of COVID-19: single compound synergized inhibition of SARS-CoV-2 replication and direct suppression of inflammatory cytokines in vitro/vivo]]** | |
| - | rystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing]]** | | + | | **888800000138** | **[[https://doi.org/10.1101/2020.10.13.337584|10.1101/2020.10.13.337584]]** | Roy A (2020) | **[[https://thebiogrid.org/225994/publication|ACIS, A Novel KepTide(tm), Binds to ACE-2 Receptor and Inhibits the Infection of SARS-CoV2 Virus in vitro in Primate Kidney Cells: Therapeutic Implications for COVID-19]]** | |
| - | | **888800000113** | **[[https://doi.org/10.1101/2020.09.01.277954|10.1101/2020.09.01.277954]]** | Bartolome A (2020) | **[[https://thebiogrid.org/223569/publication|Angiotensin converting enzyme 2 is a novel target of th | + | | **888800000139** | **[[https://doi.org/10.1101/2020.10.30.361873|10.1101/2020.10.30.361873]]** | Andring JT (2020) | **[[https://thebiogrid.org/225995/publication|Amino acid transporter B0AT1 influence on ADAM17 interactions with SARS-CoV-2 receptor ACE2 putatively expressed in intestine, kidney, and cardiomyocytes]]** | |
| - | e secretase complex]]** | | + | | **888800000140** | **[[https://doi.org/10.1101/2020.10.23.347534|10.1101/2020.10.23.347534]]** | Mellott D (2020) | **[[https://thebiogrid.org/225996/publication|A cysteine protease inhibitor blocks SARS-CoV-2 infection of human and monkey cells]]** | |
| - | | **888800000114** | **[[https://doi.org/10.1101/2020.08.31.274704|10.1101/2020.08.31.274704]]** | Guo L (2020) | **[[https://thebiogrid.org/223570/publication|Engineered Trimeric ACE2 Binds and Locks "Three-up" Spike Pro | + | | **888800000141** | **[[https://doi.org/10.1101/2020.10.06.327742|10.1101/2020.10.06.327742]]** | Kliche J (2020) | **[[https://thebiogrid.org/225997/publication|Cytoplasmic short linear motifs in ACE2 and integrin beta3 link SARS-CoV-2 host cell receptors to endocytosis and autophagy]]** | |
| - | tein to Potently Inhibit SARS-CoVs and Mutants]]** | | + | | **888800000142** | **[[https://doi.org/10.1101/2020.10.18.344622|10.1101/2020.10.18.344622]]** | Chan KK (2020) | **[[https://thebiogrid.org/225998/publication|An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants]]** | |
| - | | **888800000115** | **[[https://doi.org/10.1101/2020.09.09.289488|10.1101/2020.09.09.289488]]** | Kotani N (2020) | **[[https://thebiogrid.org/223571/publication|Candidate screening of host cell membrane proteins involve | + | | **888800000143** | **[[https://doi.org/10.1101/2020.11.01.363788|10.1101/2020.11.01.363788]]** | Sun J (2020) | **[[https://thebiogrid.org/225999/publication|Discovery of five HIV nucleoside analog reverse-transcriptase inhibitors (NRTIs) as potent inhibitors against the RNA-dependent RNA polymerase (RdRp) of SARS-CoV and 2019-nCoV]]** | |
| - | d in SARS-CoV-2 entry]]** | | + | | **888800000144** | **[[https://doi.org/10.1101/2020.10.30.362335|10.1101/2020.10.30.362335]]** | Hu Y (2020) | **[[https://thebiogrid.org/226000/publication|Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses in cell culture]]** | |
| - | | **888800000116** | **[[https://doi.org/10.1101/2020.08.27.270637|10.1101/2020.08.27.270637]]** | Flower TG (2020) | **[[https://thebiogrid.org/223572/publication|Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavi | + | | **888800000145** | **[[https://doi.org/10.1101/2020.10.11.335299|10.1101/2020.10.11.335299]]** | Gobeil S (2020) | **[[https://thebiogrid.org/226001/publication|D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction]]** | |
| - | rus protein implicated in immune evasion]]** | | + | | **888800000146** | **[[https://doi.org/10.1101/2020.10.06.327445|10.1101/2020.10.06.327445]]** | Flynn RA (2020) | **[[https://thebiogrid.org/226002/publication|Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection]]** | |
| - | | **888800000117** | **[[https://doi.org/10.1101/2020.09.21.307439|10.1101/2020.09.21.307439]]** | Wang X (2020) | **[[https://thebiogrid.org/223769/publication|Bat and pangolin coronavirus spike glycoprotein structures p | + | | **888800000147** | **[[https://doi.org/10.1101/2020.09.24.312553|10.1101/2020.09.24.312553]]** | Li Y (2020) | **[[https://thebiogrid.org/226003/publication|SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes]]** | |
| - | rovide insights into SARS-CoV-2 evolution]]** | | + | | **888800000148** | **[[https://doi.org/10.1101/2020.10.22.351569|10.1101/2020.10.22.351569]]** | Nguyen HT (2020) | **[[https://thebiogrid.org/226004/publication|Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects]]** | |
| - | | **888800000118** | **[[https://doi.org/10.1101/2020.09.14.295956|10.1101/2020.09.14.295956]]** | Lin C (2020) | **[[https://thebiogrid.org/223770/publication|Ceftazidime Is a Potential Drug to Inhibit SARS-CoV-2 Infecti | + | | **888800000149** | **[[https://doi.org/10.1101/2020.10.22.351056|10.1101/2020.10.22.351056]]** | Bojadzic D (2020) | **[[https://thebiogrid.org/226005/publication|Small-Molecule In Vitro Inhibitors of the Coronavirus Spike - ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2]]** | |
| - | on In Vitro by Blocking Spike Protein-ACE2 Interaction]]** | | + | | **888800000150** | **[[https://doi.org/10.1101/2020.10.08.20209114|10.1101/2020.10.08.20209114]]** | Wu F (2020) | **[[https://thebiogrid.org/226006/publication|Antibody-dependent enhancement (ADE) of SARS-CoV-2 infection in recovered COVID-19 patients: studies based on cellular and structural biology analysis]]** | |
| - | | **888800000119** | **[[https://doi.org/10.1101/2020.09.16.297366|10.1101/2020.09.16.297366]]** | Sagar S (2020) | **[[https://thebiogrid.org/223771/publication|Bromelain Inhibits SARS-CoV-2 Infection in VeroE6 Cells]]** | + | | **888800000151** | **[[https://doi.org/10.1101/2020.09.30.317818|10.1101/2020.09.30.317818]]** | Hsu AC-Y (2020) | **[[https://thebiogrid.org/226007/publication|SARS-CoV-2 Spike protein promotes hyper-inflammatory response that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitro]]** | |
| - | | | + | | **888800000152** | **[[https://doi.org/10.1101/2020.11.05.369264|10.1101/2020.11.05.369264]]** | Soh WT (2020) | **[[https://thebiogrid.org/226008/publication|The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN]]** | |
| - | | **888800000120** | **[[https://doi.org/10.1101/2020.09.18.301952|10.1101/2020.09.18.301952]]** | Xiao T (2020) | **[[https://thebiogrid.org/223772/publication|A trimeric human angiotensin-converting enzyme 2 as an anti- | + | |
| - | SARS-CoV-2 agent in vitro]]** | | + | |
| - | | **888800000121** | **[[https://doi.org/10.1101/2020.09.16.297945|10.1101/2020.09.16.297945]]** | Meyer B (2020) | **[[https://thebiogrid.org/223773/publication|Characterisation of protease activity during SARS-CoV-2 inf | + | |
| - | ection identifies novel viral cleavage sites and cellular targets for drug repurposing]]** | | + | |
| - | | **888800000122** | **[[https://doi.org/10.1101/2020.09.22.308338|10.1101/2020.09.22.308338]]** | Wagner TR (2020) | **[[https://thebiogrid.org/223774/publication|NeutrobodyPlex - Nanobodies to monitor a SARS-CoV-2 neutr | + | |
| - | alizing immune response]]** | | + | |
| - | | **888800000123** | **[[https://doi.org/10.1101/2020.09.20.297242|10.1101/2020.09.20.297242]]** | Ren W (2020) | **[[https://thebiogrid.org/223775/publication|Comparative analysis reveals the species-specific genetic det | + | |
| - | erminants of ACE2 required for SARS-CoV-2 entry]]** | | + | |
| - | | **888800000124** | **[[https://doi.org/10.1101/2020.09.13.295691|10.1101/2020.09.13.295691]]** | Olaleye OA (2020) | **[[https://thebiogrid.org/223776/publication|Ambroxol Hydrochloride Inhibits the Interaction between | + | |
| - | Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein's Receptor Binding Domain and Recombinant Human ACE2.]]** | | + | |
| - | | **888800000125** | **[[https://doi.org/10.1101/2020.09.16.300319|10.1101/2020.09.16.300319]]** | Tada T (2020) | **[[https://thebiogrid.org/223777/publication|A soluble ACE2 microbody protein fused to a single immunoglo | + | |
| - | bulin Fc domain is a potent inhibitor of SARS-CoV-2 infection in cell culture]]** | | + | |
| - | | **888800000126** | **[[https://doi.org/10.1101/2020.09.16.299891|10.1101/2020.09.16.299891]]** | Higuchi Y (2020) | **[[https://thebiogrid.org/223778/publication|High affinity modified ACE2 receptors prevent SARS-CoV-2 | + | |
| - | infection]]** | | + | |
| - | | **888800000127** | **[[https://doi.org/10.1101/2020.09.16.20190694|10.1101/2020.09.16.20190694]]** | Ichimura T (2020) | **[[https://thebiogrid.org/223779/publication|KIM-1/TIM-1 is a Receptor for SARS-CoV-2 in Lung and | + | |
| - | Kidney]]** | | + | |
| - | | **888800000128** | **[[https://doi.org/10.1101/2020.11.04.361154|10.1101/2020.11.04.361154]]** | de Vries (2020) | **[[https://thebiogrid.org/225841/publication|Intranasal fusion inhibitory lipopeptide prevents direct c | + | |
| - | ontact SARS-CoV-2 transmission in ferrets]]** | | + | |
| - | | **888800000129** | **[[https://doi.org/10.1101/2020.10.13.336800|10.1101/2020.10.13.336800]]** | Yan R (2020) | **[[https://thebiogrid.org/225985/publication|Structural basis for bivalent binding and inhibition of SARS- | + | |
| - | CoV-2 infection by human potent neutralizing antibodies]]** | | + | |
| - | | **888800000130** | **[[https://doi.org/10.1101/2020.09.27.315796|10.1101/2020.09.27.315796]]** | Bauer MS (2020) | **[[https://thebiogrid.org/225986/publication|A Tethered Ligand Assay to Probe the SARS-CoV-2 ACE2 Inter | + | |
| - | action under Constant Force]]** | | + | |
| - | | **888800000131** | **[[https://doi.org/10.1101/2020.10.06.328112|10.1101/2020.10.06.328112]]** | Lutomski CA (2020) | **[[https://thebiogrid.org/225987/publication|Autoproteolytic Products of the SARS-CoV-2 Nucleocapsid | + | |
| - | Protein are Primed for Antibody Evasion and Virus Proliferation]]** | | + | |
| - | | **888800000132** | **[[https://doi.org/10.1101/2020.10.31.363473|10.1101/2020.10.31.363473]]** | Stevens BR (2020) | **[[https://thebiogrid.org/225988/publication|TMPRSS2 and ADAM17 interactions with ACE2 complexed with | + | |
| - | SARS-CoV-2 and B0AT1 putatively in intestine, cardiomyocytes, and kidney]]** | | + | |
| - | | **888800000133** | **[[https://doi.org/10.1101/2020.10.23.350348|10.1101/2020.10.23.350348]]** | Tang X (2020) | **[[https://thebiogrid.org/225989/publication|Transferrin receptor is another receptor for SARS-CoV-2 entr | + | |
| - | y]]** | | + | |
| - | | **888800000134** | **[[https://doi.org/10.1101/2020.11.04.361576|10.1101/2020.11.04.361576]]** | Li W (2020) | **[[https://thebiogrid.org/225990/publication|Human Identical Sequences of SARS-CoV-2 Promote Clinical Progr | + | |
| - | ession of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network]]** | | + | |
| - | | **888800000135** | **[[https://doi.org/10.1101/2020.10.29.352450|10.1101/2020.10.29.352450]]** | Bakovic A (2020) | **[[https://thebiogrid.org/225991/publication|Brilacidin, a COVID-19 Drug Candidate, Exhibits Potent In | + | |
| - | Vitro Antiviral Activity Against SARS-CoV-2]]** | | + | |
| - | | **888800000136** | **[[https://doi.org/10.1101/2020.10.26.356048|10.1101/2020.10.26.356048]]** | Liu G (2020) | **[[https://thebiogrid.org/225992/publication|ISG15-dependent Activation of the RNA Sensor MDA5 and its Ant | + | |
| - | agonism by the SARS-CoV-2 papain-like protease]]** | | + | |
| - | | **888800000137** | **[[https://doi.org/10.1101/2020.10.16.342097|10.1101/2020.10.16.342097]]** | Gao X (2020) | **[[https://thebiogrid.org/225993/publication|Duple extinguishment of COVID-19: single compound synergized | + | |
| - | inhibition of SARS-CoV-2 replication and direct suppression of inflammatory cytokines in vitro/vivo]]** | | + | |
| - | | **888800000138** | **[[https://doi.org/10.1101/2020.10.13.337584|10.1101/2020.10.13.337584]]** | Roy A (2020) | **[[https://thebiogrid.org/225994/publication|ACIS, A Novel KepTide(tm), Binds to ACE-2 Receptor and Inhibi | + | |
| - | ts the Infection of SARS-CoV2 Virus in vitro in Primate Kidney Cells: Therapeutic Implications for COVID-19]]** | | + | |
| - | | **888800000139** | **[[https://doi.org/10.1101/2020.10.30.361873|10.1101/2020.10.30.361873]]** | Andring JT (2020) | **[[https://thebiogrid.org/225995/publication|Amino acid transporter B0AT1 influence on ADAM17 interac | + | |
| - | tions with SARS-CoV-2 receptor ACE2 putatively expressed in intestine, kidney, and cardiomyocytes]]** | | + | |
| - | | **888800000140** | **[[https://doi.org/10.1101/2020.10.23.347534|10.1101/2020.10.23.347534]]** | Mellott D (2020) | **[[https://thebiogrid.org/225996/publication|A cysteine protease inhibitor blocks SARS-CoV-2 infection | + | |
| - | of human and monkey cells]]** | | + | |
| - | | **888800000141** | **[[https://doi.org/10.1101/2020.10.06.327742|10.1101/2020.10.06.327742]]** | Kliche J (2020) | **[[https://thebiogrid.org/225997/publication|Cytoplasmic short linear motifs in ACE2 and integrin beta3 | + | |
| - | link SARS-CoV-2 host cell receptors to endocytosis and autophagy]]** | | + | |
| - | | **888800000142** | **[[https://doi.org/10.1101/2020.10.18.344622|10.1101/2020.10.18.344622]]** | Chan KK (2020) | **[[https://thebiogrid.org/225998/publication|An engineered decoy receptor for SARS-CoV-2 broadly binds p | + | |
| - | rotein S sequence variants]]** | | + | |
| - | | **888800000143** | **[[https://doi.org/10.1101/2020.11.01.363788|10.1101/2020.11.01.363788]]** | Sun J (2020) | **[[https://thebiogrid.org/225999/publication|Discovery of five HIV nucleoside analog reverse-transcriptase | + | |
| - | inhibitors (NRTIs) as potent inhibitors against the RNA-dependent RNA polymerase (RdRp) of SARS-CoV and 2019-nCoV]]** | | + | |
| - | | **888800000144** | **[[https://doi.org/10.1101/2020.10.30.362335|10.1101/2020.10.30.362335]]** | Hu Y (2020) | **[[https://thebiogrid.org/226000/publication|Boceprevir, calpain inhibitors II and XII, and GC-376 have bro | + | |
| - | ad-spectrum antiviral activity against coronaviruses in cell culture]]** | | + | |
| - | | **888800000145** | **[[https://doi.org/10.1101/2020.10.11.335299|10.1101/2020.10.11.335299]]** | Gobeil S (2020) | **[[https://thebiogrid.org/226001/publication|D614G mutation alters SARS-CoV-2 spike conformational dyna | + | |
| - | mics and protease cleavage susceptibility at the S1/S2 junction]]** | | + | |
| - | | **888800000146** | **[[https://doi.org/10.1101/2020.10.06.327445|10.1101/2020.10.06.327445]]** | Flynn RA (2020) | **[[https://thebiogrid.org/226002/publication|Systematic discovery and functional interrogation of SARS- | + | |
| - | CoV-2 viral RNA-host protein interactions during infection]]** | | + | |
| - | | **888800000147** | **[[https://doi.org/10.1101/2020.09.24.312553|10.1101/2020.09.24.312553]]** | Li Y (2020) | **[[https://thebiogrid.org/226003/publication|SARS-CoV-2 induces double-stranded RNA-mediated innate immune | + | |
| - | responses in respiratory epithelial derived cells and cardiomyocytes]]** | | + | |
| - | | **888800000148** | **[[https://doi.org/10.1101/2020.10.22.351569|10.1101/2020.10.22.351569]]** | Nguyen HT (2020) | **[[https://thebiogrid.org/226004/publication|Spike glycoprotein and host cell determinants of SARS-CoV | + | |
| - | -2 entry and cytopathic effects]]** | | + | |
| - | | **888800000149** | **[[https://doi.org/10.1101/2020.10.22.351056|10.1101/2020.10.22.351056]]** | Bojadzic D (2020) | **[[https://thebiogrid.org/226005/publication|Small-Molecule In Vitro Inhibitors of the Coronavirus Sp | + | |
| - | ike - ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2]]** | | + | |
| - | | **888800000150** | **[[https://doi.org/10.1101/2020.10.08.20209114|10.1101/2020.10.08.20209114]]** | Wu F (2020) | **[[https://thebiogrid.org/226006/publication|Antibody-dependent enhancement (ADE) of SARS-CoV-2 infecti | + | |
| - | on in recovered COVID-19 patients: studies based on cellular and structural biology analysis]]** | | + | |
| - | | **888800000151** | **[[https://doi.org/10.1101/2020.09.30.317818|10.1101/2020.09.30.317818]]** | Hsu AC-Y (2020) | **[[https://thebiogrid.org/226007/publication|SARS-CoV-2 Spike protein promotes hyper-inflammatory respo | + | |
| - | nse that can be ameliorated by Spike-antagonistic peptide and FDA-approved ER stress and MAP kinase inhibitors in vitro]]** | | + | |
| - | | **888800000152** | **[[https://doi.org/10.1101/2020.11.05.369264|10.1101/2020.11.05.369264]]** | Soh WT (2020) | **[[https://thebiogrid.org/226008/publication|The N-terminal domain of spike glycoprotein mediates SARS-Co | + | |
| - | V-2 infection by associating with L-SIGN and DC-SIGN]]** | | + | |