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--- biogrid_mv [2015/10/29 15:53]
biogridadmin [BioGRID Multi-Validated (MV) Datasets]
+++ biogrid_mv [2017/08/08 12:52]
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-====== BioGRID Multi-Validated (MV) Datasets ======
-BioGRID multi-validated datasets (MV) contain physical interactions that pass a specific set of criteria. This criteria is outlined below:
-[[downloads|Back to BioGRID Download Formats]]
-==== Multi-Validation Criteria ====
-A physical interaction with participants **A** and **B** with a specific **Experimental System** and **Publication Source** is considered multi-validated if:
-  - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with the same **Publication Source** but a different **Experimental System**
-  - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with the same **Experimental System** but a different **Publication Source**
-  - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with a different **Experimental System** and a different **Publication Source**
-Genetic interactions are excluded and physical interactions not passing this criteria are excluded. Also, the following datasets were combined and treated as one dataset to prevent self-validation.
-- [[http://thebiogrid.org/15270/publication/high-definition-macromolecular-composition-of-yeast-rna-processing-complexes.html|Krogan NJ (2004)]], [[http://thebiogrid.org/21816/publication/global-landscape-of-protein-complexes-in-the-yeast-saccharomyces-cerevisiae.html|Krogan NJ (2006)]], [[http://thebiogrid.org/21817/publication/proteome-survey-reveals-modularity-of-the-yeast-cell-machinery.html|Gavin AC (2006)]], [[http://thebiogrid.org/70702/publication/toward-a-comprehensive-atlas-of-the-physical-interactome-of-saccharomyces-cerevisiae.html|Collins SR (2007)]]
-[[downloads|Back to BioGRID Download Formats]]