BioGRID Multi-Validated (MV) Datasets
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- | ====== BioGRID Multi-Validated (MV) Datasets ====== | ||
- | BioGRID multi-validated datasets (MV) contain physical interactions that pass a specific multi-validation set of criteria. This criteria is outlined below: | ||
- | [[downloads|Back to BioGRID Download Formats]] | ||
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- | ==== Multi-Validation Criteria ==== | ||
- | A physical interaction with participants **A** and **B** with a specific **Experimental System** and **Publication Source** is considered multi-validated if: | ||
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- | - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with the same **Publication Source** but a different **Experimental System** | ||
- | - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with the same **Experimental System** but a different **Publication Source** | ||
- | - There is another physical interaction in BioGRID where **A** -> **B** or **B** -> **A** with a different **Experimental System** and a different **Publication Source** | ||
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- | Genetic interactions are excluded and physical interactions not passing this criteria are excluded. Also, the following datasets were combined and treated as one dataset to prevent self-validation. | ||
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- | - [[http://thebiogrid.org/15270/publication/high-definition-macromolecular-composition-of-yeast-rna-processing-complexes.html|Krogan NJ (2004)]], [[http://thebiogrid.org/21816/publication/global-landscape-of-protein-complexes-in-the-yeast-saccharomyces-cerevisiae.html|Krogan NJ (2006)]], [[http://thebiogrid.org/21817/publication/proteome-survey-reveals-modularity-of-the-yeast-cell-machinery.html|Gavin AC (2006)]], [[http://thebiogrid.org/70702/publication/toward-a-comprehensive-atlas-of-the-physical-interactome-of-saccharomyces-cerevisiae.html|Collins SR (2007)]] | ||
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- | [[downloads|Back to BioGRID Download Formats]] |