About the BioGRID
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Table of Contents
About the BioGRID
The Biological General Repository for Interaction Datasets (BioGRID) database (http://www.thebiogrid.org) was developed to house and distribute collections of protein and genetic interactions from major model organism species. BioGRID currently contains over 250,000 interactions from major model organism species, as derived from both high-throughput studies and conventional focused studies. Through comprehensive curation efforts, BioGRID now includes a virtually complete set of interactions reported to date in the primary literature for the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe. A number of new features have been added to the BioGRID including an improved user interface to display interactions based on different attributes, a mirror site and a dedicated interaction management system to coordinate curation across different locations. The BioGRID provides interaction data with monthly updates to Saccharomyces Genome Database, Flybase and Entrez Gene. Source code for the BioGRID and the linked Osprey network visualization system is now freely available without restriction.
Contact Information
- EMAIL: biogridadmin@gmail.com
- FAX: Attention BIOGRID Administrator C/O Mike Tyers @ 416-586-8869
BioGRID Team
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- Lorrie Boucher [curator, Toronto]
- Bobby-Joe Breitkretuz [software engineer, Toronto]
- Andrew Chatr-Aryamontri [curator, Edinburgh]
- Kara Dolinski [co-principal investigator, Princeton]
- Michael Livstone [curator, Princeton]
- Julie Nixon [curator, Edinburgh]
- Rose Oughtred [curator, Princeton]
- Teresa Reguly [curator, Toronto]
- Jennifer Rust [curator, Princeton]
- Chris Stark [software engineer, Toronto]
- Mike Tyers [principal investigator, Edinburgh]
- Andrew Winter [curator, Edinburgh]
BioGRID Funding
BioGRID Publications
- Breitkreutz BJ, Stark C, Reguly T, Boucher L, Breitkreutz A, Livstone M, Oughtred R, Lackner DH, Bähler J, Wood V, Dolinski K, Tyers M. The BioGRID Interaction Database: 2008 update. Nucleic Acids Res. 2008 Jan;36(Database issue):D637-40. Epub 2007 Nov 13. [ Pubmed ]
- Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hon GC, Myers CL, Parsons A, Friesen H, Oughtred R, Tong A, Stark C, Ho Y, Botstein D, Andrews B, Boone C, Troyanskya OG, Ideker T, Dolinski K, Batada NN, Tyers M. Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. J Biol. 2006;5(4):11. Epub 2006 Jun 8. [ Pubmed ]
- Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M. BioGRID: a general repository for interaction datasets. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D535-9. [ Pubmed ]
- Breitkreutz BJ, Stark C, Tyers M. The GRID: the General Repository for Interaction Datasets. Genome Biol. 2003;4(3):R23. Epub 2003 Feb 27. [ Pubmed ]
- Breitkreutz BJ, Stark C, Tyers M. Osprey: a network visualization system. Genome Biol. 2003;4(3):R23. Epub 2003 Feb 27. [ Pubmed ]
BioGRID Affiliations
