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- aboutus [2015/01/06 22:53] biogridadmin [BioGRID Team]
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+ aboutus [2023/10/16 15:39] (current) biogridadmin [BioGRID Team]
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 ====== About the BioGRID ======
 
 The Biological General Repository for Interaction Datasets (BioGRID) is a public database that archives and disseminates genetic and protein interaction data from model organisms and humans (**[[httphttps://​thebiogrid.org|thebiogrid.org]]**). BioGRID currently holds over **[[statistics|7801,740,000 interactions]]** curated from both high-throughput datasets and individual focused studies, as derived from over 4370,000publications in the primary literature. Complete coverage of the entire literature is maintained for budding yeast (S. cerevisiae),​ fission yeast (S. pombe) and thale cress (A. thaliana), and efforts to expand curation across multiple metazoan species are underway. Current curation drives are focused on particular areas of biology to enable insights into conserved networks and pathways that are relevant to human health. The BioGRID 3.web interface contains new search and display features that enable rapid queries across multiple data types and sources. BioGRID provides interaction data to several model organism databases, resources such as **[[http://​www.ncbi.nlm.nih.gov/​gene|Entrez-Gene]]**,​ **[[http://​www.yeastgenome.org/​|SGD]]**,​ **[[http://​www.arabidopsis.org/​|TAIR]]**,​ **[[http://​flybase.org/​|FlyBase]]** and other **[[httphttps://​wiki.thebiogrid.org/​doku.php/​partners|interaction meta-databases]]**. The entire BioGRID 3.2 data collection may be **[[http://​thebiogrid.org/​download.php|downloaded in multiple file formats]]**,​ including **[[http://​www.imexconsortium.org|IMEx]]** compatible PSI MI XML. For developers, BioGRID interactions are also available via a **[[biogridrest|REST based Web Service]]** and **[[biogridplugin2|Cytoscape plugin]]**. All BioGRID documentation is available online in the **[[httphttps://​wiki.thebiogrid.org|BioGRID Wiki]]**.
 
 ** Contact Information **
   * **EMAIL**: **[[biogridadminsupport@gmailthebiogrid.comorg]]**
   * **TWITTER**:​ **[[http://​twitter.com/#​!/​biogrid|@biogrid]]**
   * **YOUTUBE**:​ **[[https://​www.youtube.com/​channel/​UCIdwfNwL9gi4oLBUqDB189g|BioGRID]]**
   * **GITHUB**: **[[https://​github.com/​BioGRID|BioGRID]]**
 ===== BioGRID Team =====
   * **Lorrie Boucher** [curator, Toronto][[http://​www.princeton.edu/​main/​|{{ :​princeton_university.gif.png|}}]] 
   * **Ashton Breitkreutz** [curator, Toronto]
   * **Bobby-Joe Breitkreutz** [software engineer, Toronto]
   * **Christie Chang** [curator, Princeton]
   * **Andrew Chatr-Aryamontri** [curator, Montreal][[http://​www.iric.ca/​|{{ :​universityofmontreal.jpg|}}]] 
   * **Daici Chen** [curator, Montreal]
   * **Kara Dolinski** [co-principal investigator,​ Princeton]
   * **Sven Heinicke** [software engineer, Princeton] 
   * **Jodi HirschmanSonam Dolma** [curator, ​PrincetonToronto
   * **Nadine Kolas** [curator, Toronto][[http://​www.ed.ac.uk/​home|{{ :​edinburgh.jpg|}}]
   * **Julie NixonGenie Leung** [curator, ​EdinburghToronto]
   * **Lara O’Donnell** [curator, Toronto]
   * **Rose Oughtred** [curator, Princeton]
   * **Jennifer Rust** [curator, Princeton][[http://​www.lunenfeld.ca/​|{{ :​slri_logo.gif|}}]] 
   * **Adnane Sellam** [curator, Laval]
   * **Chris Stark** [software engineer, Toronto]
   * **Chandra Theesfeld** [curator, Princeton]
   * **Mike Tyers** [principal investigator,​ Montreal]
   * **Andrew Willems** [curator, Toronto]
   * **Frederick Zhang** [curator, Toronto]
   ​
 
 ==== Alumni ====
   * **Ashton Breitkreutz** [curator, Toronto]
   * **Daici Chen** [curator, Montreal] ​
   * **Sven Heinicke** [software engineer, Princeton]
   * **Jodi Hirschman** [curator, Princeton]
   * **Michael Livstone** [curator, Princeton]
   * **Rochelle McAdam** [curator, Toronto]
   * **Julie Nixon** [curator, Edinburgh]
   * **Sara Oster** [curator, Toronto]
   * **Lindsay Ramage** [curator, Edinburgh]
   * **Teresa Reguly** [curator, Toronto]
   * **Adnane Sellam** [curator, Montreal]
   * **Jean Tang** [curator, Toronto]
   * **Chandra Theesfeld** [curator, Princeton]
   * **Andrew Winter** [curator, Edinburgh]
 
 ===== BioGRID Funding =====
 
 [[httphttps://wwworip.nih.gov/​|{{:​nihnih_orip.png|}}]][[http://​www.cihr-irsc.gc.ca/​|{{:​cihr_logo_big_e.png?​315|}}]][[http://​www.bbsrc.ac.uk/​|{{ :​new_bbsrc_colour.gif?315225|}}]]
 
 NIH - **#R01 RR024031**
 ===== BioGRID Publications =====
 
 {{ :newsnewspaper.png|}} 
   * Oughtred R, Rust J, Chang C, Breitkreutz BJ, Stark C, Willems A, Boucher L, Leung G, Kolas N, Zhang F, Dolma S, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M. **The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions**. ​ Protein Sci. 2020 Oct 18. [ [[https://​pubmed.ncbi.nlm.nih.gov/​33070389/​|Pubmed]],​ [[https://​doi.org/​10.1002/​pro.3978|Protein Science]] ] 
   * Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O'​Donnell L, Leung G, McAdam R, Zhang F, Dolma S, Willems A, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M. **The BioGRID interaction database: 2019 update**. Nucleic Acids Res. 2019 Jan 8;​47(D1):​D529-D541 [ [[https://​www.ncbi.nlm.nih.gov/​pubmed/​30476227|Pubmed]],​ [[https://​academic.oup.com/​nar/​article/​47/​D1/​D529/​5204333|NAR]] ] 
   * Chatr-Aryamontri A, Oughtred R, Boucher L, Rust J, Chang C, Kolas NK, O'​Donnell L, Oster S, Theesfeld C, Sellam A, Stark C, Breitkreutz BJ, Dolinski K, Tyers M. **The BioGRID interaction database: 2017 update**. Nucleic Acids Res. 2016 Dec 14;2017(1) [ [[https://​www.ncbi.nlm.nih.gov/​pubmed/​27980099|Pubmed]],​ [[http://​nar.oxfordjournals.org/​content/​45/​D1/​D369|NAR]] ] 
   * Oughtred R, Chatr-Aryamontri A, Breitkreutz BJ, Chang CS, Rust JM, Theesfeld CL, Heinicke S, Breitkreutz A, Chen D, Hirschman J, Kolas N, Livstone MS, Nixon J, O'​Donnell L, Ramage L, Winter A, Reguly T, Sellam A, Stark C, Boucher L, Dolinski K, Tyers M. **Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions**. Cold Spring Harb Protoc. 2016 Jan 4;​2016(1):​pdb.prot088880 [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​26729909|Pubmed]] ]  
   * Oughtred R, Chatr-Aryamontri A, Breitkreutz BJ, Chang CS, Rust JM, Theesfeld CL, Heinicke S, Breitkreutz A, Chen D, Hirschman J, Kolas N, Livstone MS, Nixon J, O'​Donnell L, Ramage L, Winter A, Reguly T, Sellam A, Stark C, Boucher L, Dolinski K, Tyers M. **BioGRID: A Resource for Studying Biological Interactions in Yeast**. Cold Spring Harb Protoc. 2016 Jan 4;​2016(1):​pdb.top080754 [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​26729913|Pubmed]] ]  
   * Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M. **Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning.** Cell Systems. Dec. 23, 2015, 1(6):​383-95. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​27136353|Pubmed]] ]
   * Chatr-Aryamontri A, Breitkreutz BJ, Oughtred R, Boucher L, Heinicke S, Chen D, Stark C, Breitkreutz A, Kolas N, O'​Donnell L, Reguly T, Nixon J, Ramage L, Winter A, Sellam A, Chang C, Hirschman J, Theesfeld C, Rust J, Livstone MS, Dolinski K, Tyers M. **The BioGRID interaction database: 2015 update.** Nucleic Acids Research. Nov. 2014, [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​25428363|Pubmed]] ] 
   * Sadowski I, Breitkreutz BJ, Stark C, Su TC, Dahabieh M, Raithatha S, Bernhard W, Oughtred R, Dolinski K, Barreto K, Tyers M. **The PhosphoGRID Saccharomyces cerevisiae Protein Phosphorylation Site Database: Version 2.0 Update.** Database (Oxford) May 2013; [ [[http://​www.ncbi.nlm.nih.gov/​pmc/​articles/​PMC3653121/​|Pubmed]] ] 
   * Chatr-Aryamontri A, Breitkreutz BJ, Heinicke S, Boucher L, Winter A, Stark C, Nixon J, Ramage L, Kolas N, O'​Donnell L, Reguly T, Breitkreutz A, Sellam A, Chen D, Chang C, Rust JM, Livstone MS, Oughtred R, Dolinski K, Tyers M. **The BioGRID Interaction Database: 2013 update.** Nucleic Acids Res. 2012 Nov 30. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​23203989|Pubmed]] ]
   * Winter AG, Wildenhain J, Tyers M. **BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID.** Bioinformatics,​ 2011 Apr 1. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​21300700|Pubmed]] ]
   * Stark C, Breitkreutz BJ, Chatr-Aryamontri A, Boucher L, Oughtred R, Livstone MS, Nixon J, Van Auken K, Wang X, Shi X, Reguly T, Rust JM, Winter A, Dolinski K, Tyers M. **The BioGRID Interaction Database: 2011 update.** Nucleic Acids Res. 2010 Nov 11. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​21071413|Pubmed]] ]
   * Breitkreutz A, Choi H, Sharom JR, Boucher L, Neduva V, Larsen B, Lin ZY, Breitkreutz BJ, Stark C, Liu G, Ahn J, Dewar-Darch D, Reguly T, Tang X, Almeida R, Qin ZS, Pawson T, Gingras AC, Nesvizhskii AI, Tyers M.  **A global protein kinase and phosphatase interaction network in yeast.** Science. 2010 May 21;​328(5981):​1043-6. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​20489023|Pubmed]] ]
@@ Line -52,39 +69,15 @@ removed created
   * Breitkreutz BJ, Stark C, Tyers M. **The GRID: the General Repository for Interaction Datasets.** Genome Biol. 2003;​4(3):​R23. Epub 2003 Feb 27. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​12620108|Pubmed]] ]
   * Breitkreutz BJ, Stark C, Tyers M. **Osprey: a network visualization system.** Genome Biol. 2003;​4(3):​R23. Epub 2003 Feb 27. [ [[http://​www.ncbi.nlm.nih.gov/​pubmed/​12620107|Pubmed]] ]
 
 ===== BioGRID Affiliations =====
 {{ globe2.png}}
   * [[httphttps://​www.systemsbiology.org/​scientists_and_researchpeople/Faculty_Groupsfaculty/​aitchison-lab/Aitchison_Group|John Aitchison Lab]]  
   *    ​| ​[[http://wwwsites.utoronto.ca/​andrewslab/​people.shtml|Brenda Andrews Lab]]  
   *     | [[http://​baderlab.org/​Home|Gary Bader Lab]]  
   *        ​| ​[[http://​www.bahlerlab.info/​|Jürg Bähler Lab]]    | 
  ​* ​[[httphttps://researchwww.jax.org/research-and-faculty/judith_blake.htmlresearch-labs/​the-blake-lab|Judy Blake Lab]]  
   *    ​| ​[[http://​www.bs.jhmi.edu/​MBG/​boekelab/​|Jef Boeke Lab]]  
   *     | [[http://wwwsites.utoronto.ca/​boonelab/​|Charlie Boone Lab]]  
   *        ​| ​[[http://​www.princeton.edu/​genomics/​botstein/​|David Botstein Lab]]    | 
  ​* ​[[http://​mint.bio.uniroma2.it/​mint/​Welcome.do|Gianni Cesarini Lab]]  
   *    ​| ​[[httphttps://medcherrylab.stanford.edu/​profiles/​frdActionServlet?​choiceId=printerprofile&​fid=4249|Mike Cherry Lab]]  
   *     | [[http://​proteome.wayne.edu/​finlabindexindex.html|Russ Finley Lab]]  
   *      ​| ​[[http://​www.embl.de/​research/​units/​scb/​gavin/​members/?​s_personId=4074|Anne-Claude Gavin Lab]]    | 
  ​* ​[[http://golgivirus.harvardchem.ucla.edu/faculty/​faculty_profile.php?​f=william-gelbart-m|Bill Gelbart Lab]]  
   *    ​| ​[[http://​gingraslab.lunenfeld.ca|Anne-Claude Gingras Lab]]  
   *     | [[http://​www.ebi.ac.uk/​~hhe/​|Henning Hermjakob Lab]]  
   *      ​| ​[[http://carnegiedpbwww.stanfordarabidopsis.eduorg/contentabout/huala-labstaff.jsp|Eva Huala Lab]]    | 
  ​* ​[[http://​chianti.ucsd.edu/​idekerlab/​|Trey Ideker Lab]]  
   *    ​| ​[[httphttps://viromicsharper.washingtonhms.harvard.edu/|Michael Katze Wade Harper ​Lab]]  
   *    ​| ​[[http://www.morrislab.med.utoronto.ca/|Quaid Morris Lab]]  
   *      ​| ​[[http://​pawsonlab.mshri.on.ca/​|Tony Pawson Lab]]    | 
  ​* ​[[http://​www.bc.biol.ethz.ch/​peopleresearch/groupspeter/petermpeople/​matthias-peter.html|Matthias Peter Lab]]  
   *    ​| ​[[httphttps://labs.oicr.on.ca/research/​ouellette/​francis-lab|Francis Ouellette Lab]]  
   *     | [[httphttps://carnegiedpbdpb.stanfordcarnegiescience.edu/labs/​rhee-lab|Sue Rhee Lab]]  
   *      ​| ​[[http://www.biochem.ubc.ca/​fac_researchperson/facultyivan-sadowski/sadowski.html|Ivan Sadowski Lab]]    | 
  ​* ​[[http://cbiowww.mskccsanderlab.org/people#/info/​chris_sander.html|Chris Sander Lab]]  
   *    ​| ​[[http://​fafner.stanford.edu/​~sherlock/​|Gavin Sherlock Lab]]  
   *     | [[http://wwwsnyderlab.yalestanford.edu/snyder/|Mike Snyder Lab]]  
   *      ​| ​[[httphttps://steinlabs.cshloicr.orgon.ca/stein-lab|Lincoln Stein Lab]]    | 
  ​* ​[[http://​wormlab.caltech.edu/​|Paul Sternberg Lab]]  
   * [[http://​imperio.princeton.edu/​cm/​node/​13   Olga Troyanskaya Lab]] 
   * [[http://​www.cnio.es/​ing/​grupos/​plantillas/​curriculum.asp?​pag=1002|Alfonso Valencia Lab]]  
   *     | [[http://www.neuroion.uoregon.edu/​westerfcontent/lab.htmlwesterfield-laboratory|Monte Westerfield Lab]]  
   *      ​| ​[[http://biochemistrywodaklab.utoronto.caorg/wodakws/bch.html|Shoshana Wodak Lab]]    | 
  ​* ​[[http://kinaseresearch.uhnres.utorontolunenfeld.ca/woodgett/|Jim Woodgett Lab]]  
   *    |[[http://webyaffelab.mit.edu/biology|Mike Yaffe Lab]]  | [[http:/www/facultyareas/​facresearch/​yaffefunction.htmlprinceton.edu/​|Mike Yaffe Olga Troyanskaya ​Lab]]    ​| ​    | 
 
aboutus.1420602792.txt.gz · Last modified: 2017/08/08 12:52 (external edit)