======Online Tools and Resources====== Listed on this page are tools, software, and related resources either written by the BioGRID team or a third party that can help you make use of BioGRID ORCS CRISPR Screen Data. If you know of a useful software tool that should be in this listing, let us know at biogridadmin@gmail.com. ===== Partner Resources ===== * **[[https://thebiogrid.org|BioGRID]]** - The BioGRID is an interaction repository with data compiled through comprehensive curation efforts. * **[[https://yeastkinome.org|Yeast Kinome]]** - Saccharomyces cerevisiae Kinase and Phosphatase Interactome (KPI) Resource. * **[[http://prohitsms.com/|ProHits]]** - Prohits is a laboratory information management system for processing large scale mass spectrometry experiments. Prohits is closely integrated with the BioGRID providing real-time comparisons between experimental results and published interactions. * **[[https://orcsws.thebiogrid.org/|BioGRID ORCS Web Service]]** - BioGRID ORCS CRISPR screen data is available programmatically over HTTP through a REST-style web service. * **[[https://gene-info.org/|Gene Info eXtension (GIX)]]** - GIX is a browser extension that allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession. ===== Recommended CRISPR Resources ===== * **[[https://www.addgene.org/crispr/|Addgene]]** - Addgene is a global, nonprofit repository that was created to help scientists share plasmids. *Their informative e-book on the basics of CRISPR, CRISPR 101, can be found [[https://info.addgene.org/download-addgenes-ebook-crispr-101-2nd-edition?_ga=2.54860587.1876593193.1570730310-1991334409.1569343487|here]]. *Check out their blog post with an introductory overview to BioGRID ORCS **[[https://blog.addgene.org/the-open-repository-of-crispr-screens]]**. * **[[https://www.synthego.com/|Synthego]]** - Synthego is a company that provides support and products for every step of the genome engineering process. * **[[https://github.com/davidliwei/awesome-CRISPR|Awesome-CRISPR]]** - Regularly updated list of software/websites/databases/papers for genome engineering, including (but not limited to) guide design, genome editing outcome, screening analysis, etc. * **[[https://github.com/wujood/ScreenHCA|ScreenHCA]]** - A python script to cluster CRISPR screens from the BioGRID ORCS database using hierarchical clustering.