BioGRID ORCS Featured Datasets

The following is a small selection of featured datasets contributed to BioGRID ORCS. This is a good place to get started browsing the site to get used to the layout and features provided. If you have a dataset and would like to have it featured, or simply know of a great paper that the BioGRID ORCS community would appreciate seeing featured, contact us at support@thebiogrid.org to make your request.

BioGRID Featured Datasets

2021 Datasets

Hundley FV et al. - A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis, Molecular Cell, Jan. 2021.

2020 Datasets

Wang R et al. - Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses. BioRxiv Preprint. Sept. 2020.
Dhoonmoon A et al. - Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR. Nucleic Acids Research. July, 2020.
Labeau A et al. - A Genome-Wide CRISPR-Cas9 Screen Identifies the Dolichol-Phosphate Mannose Synthase Complex as a Host Dependency Factor for Dengue Virus Infection. Journal of virology. March, 2020.

2019 Datasets

Zhuang X et al. - Genome-Wide CRISPR Screen Reveals Cancer Cell Resistance to NK Cells Induced by NK-Derived IFN-γ. Frontiers in immunology. January, 2019.
Behan FM et al. - Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens. Nature. April 10, 2019.
MacLeod G et al. - Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells. Cell Reports. April 16, 2019

2018 Datasets

Pan D et al. - A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing. Science. February 2, 2018.
Haney MS et al. - Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens. Nature genetics. December, 2018.

2017 Datasets

Bertomeu T et al. - A high resolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome. Molecular and Cellular Biology. October 16, 2017.
Meyers RM et al. - Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. Nature Genetics. December 1, 2017.