====== BioGRID ORCS Featured Datasets ======
The following is a small selection of featured datasets contributed to BioGRID ORCS. This is a good place to get started browsing the site to get used to the layout and features provided. If you have a dataset and would like to have it featured, or simply know of a great paper that the BioGRID ORCS community would appreciate seeing featured, contact us at **[[support@thebiogrid.org]]** to make your request.

=====BioGRID Featured Datasets=====

==== 2021 Datasets ====
  * **[[https://orcs.thebiogrid.org/Dataset/466|Hundley FV et al.]]** - **A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis**, Molecular Cell, Jan. 2021.

==== 2020 Datasets ====
  * **[[https://orcs.thebiogrid.org/Dataset/339C|Wang R et al.]]** - **Functional genomic screens identify human host factors for SARS-CoV-2 and common cold coronaviruses.** BioRxiv Preprint. Sept. 2020.
  * **[[https://orcs.thebiogrid.org/Dataset/268|Dhoonmoon A et al.]]** - **Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR.** Nucleic Acids Research. July, 2020.
  * **[[https://orcs.thebiogrid.org/Dataset/258|Labeau A et al.]]** - **A Genome-Wide CRISPR-Cas9 Screen Identifies the Dolichol-Phosphate Mannose Synthase Complex as a Host Dependency Factor for Dengue Virus Infection.** Journal of virology. March, 2020.

==== 2019 Datasets ====
  * **[[https://orcs.thebiogrid.org/Dataset/210|Zhuang X et al.]]** - **Genome-Wide CRISPR Screen Reveals Cancer Cell Resistance to NK Cells Induced by NK-Derived IFN-γ.** Frontiers in immunology. January, 2019.
  * **[[https://orcs.thebiogrid.org/Dataset/114|Behan FM et al.]]** - **Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.** Nature. April 10, 2019.
  * **[[https://orcs.thebiogrid.org/Dataset/152|MacLeod G et al.]]** - **Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells.** Cell Reports. April 16, 2019

==== 2018 Datasets ====
  * **[[https://orcs.thebiogrid.org/Dataset/65|Pan D et al.]]** - **A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing.** Science. February 2, 2018.
  * **[[https://orcs.thebiogrid.org/Dataset/246|Haney MS et al.]]** - **Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.** Nature genetics. December, 2018.

==== 2017 Datasets ====
  * **[[https://orcs.thebiogrid.org/Dataset/22|Bertomeu T et al.]]** - **A high resolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome.** Molecular and Cellular Biology. October 16, 2017.
  * **[[https://orcs.thebiogrid.org/Dataset/41|Meyers RM et al.]]** - **Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.** Nature Genetics. December 1, 2017.