Definitions for commonly used terms
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| **CRISPRi/Inhibtion Library **-A gRNA library used in conjunction with a modified Cas enzyme fused to protein domains that turn gene expression off, thereby repressing or inhibiting gene expression without knocking the gene out. | **CRISPRi/Inhibtion Library **-A gRNA library used in conjunction with a modified Cas enzyme fused to protein domains that turn gene expression off, thereby repressing or inhibiting gene expression without knocking the gene out. | ||
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| - | **CRISPRgbc/Barcode Library **-Barcoded libraries include large numbers of unique barcodes for marking individual cells. The barcodes are passed down to daughter cells and are useful for lineage tracing or for studying the dynamics of heterogeneous tumors. | ||
| **Analytical Method **-The statistical or computational method used by the authors to determine which genes in their screen represent hits. These can range from straight-forward read counts to very complex scoring systems with associated confidence values. For a detailed list of the analytical methods currently in ORCS and the relevant references for these methods go [[orcs:controlled_vocabulary6|here]] | **Analytical Method **-The statistical or computational method used by the authors to determine which genes in their screen represent hits. These can range from straight-forward read counts to very complex scoring systems with associated confidence values. For a detailed list of the analytical methods currently in ORCS and the relevant references for these methods go [[orcs:controlled_vocabulary6|here]] | ||