====== Experimental Setup Terms ====== ^ Term ^ Description ^ ^ Drug exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to any substance which when absorbed into a living organism may modify one or more of its functions. | ^ Timecourse | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system for a specific length of time with no additional selection pressure. | ^ Exposure to different carbon sources | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being assayed for ability to use various compounds as carbon sources. | ^ Toxin exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a poisonous substance produced by a biological organism such as a microbe, animal or plant. | ^ Virus exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a minute infectious agents whose genomes are composed of DNA or RNA. | ^ Ligand Exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a molecule known to bind a target protein in the cell likely resulting in modulation of a specific signaling cascade. | ^ T cell exposure | Cells are grown in the presence of a two cell-type (2CT) CRISPR system involving human T cells as effectors and other cell types as targets in order to identify genes essential for the effector function of T cells (EFT).| ^ Implantation to mouse model | Cells are grown in the presence of a CRISPR based gene/genome engineering system and then implanted into a mouse model, generally to ascertain effect on viability or cancer development of the mouse. | ^ Other | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to other conditions, details of which are given in the notes. | [[:orcs:curation_guide|Back to ORCS Curation Guide]]