Experimental Setup Terms
Differences
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orcs:controlled_vocabulary2 [2019/06/27 09:30] jenn created |
orcs:controlled_vocabulary2 [2022/07/12 17:48] (current) jenn |
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- | ====== Expreimental Setup Terms ====== | + | ====== Experimental Setup Terms ====== |
^ Term ^ Description ^ | ^ Term ^ Description ^ | ||
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^ Toxin exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a poisonous substance produced by a biological organism such as a microbe, animal or plant. | | ^ Toxin exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a poisonous substance produced by a biological organism such as a microbe, animal or plant. | | ||
^ Virus exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a minute infectious agents whose genomes are composed of DNA or RNA. | | ^ Virus exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a minute infectious agents whose genomes are composed of DNA or RNA. | | ||
- | ^ Ligand Exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a molecule known to bind a target protein in the cell likely resulting in modulation of a specific signalling cascade. | | + | ^ Ligand Exposure | Organisms or cells are grown in the presence of a CRISPR based gene/genome engineering system while also being subjected to a molecule known to bind a target protein in the cell likely resulting in modulation of a specific signaling cascade. | |
^ T cell exposure | Cells are grown in the presence of a two cell-type (2CT) CRISPR system involving human T cells as effectors and other cell types as targets in order to identify genes essential for the effector function of T cells (EFT).| | ^ T cell exposure | Cells are grown in the presence of a two cell-type (2CT) CRISPR system involving human T cells as effectors and other cell types as targets in order to identify genes essential for the effector function of T cells (EFT).| | ||
^ Implantation to mouse model | Cells are grown in the presence of a CRISPR based gene/genome engineering system and then implanted into a mouse model, generally to ascertain effect on viability or cancer development of the mouse. | | ^ Implantation to mouse model | Cells are grown in the presence of a CRISPR based gene/genome engineering system and then implanted into a mouse model, generally to ascertain effect on viability or cancer development of the mouse. | |