http://wiki.thebiogrid.org/ 2010-09-06T19:03:50-04:00 http://wiki.thebiogrid.org/ http://wiki.thebiogrid.org/lib/images/favicon.ico text/html 2010-06-01T11:15:06-04:00 http://wiki.thebiogrid.org/doku.php/aboutus?rev=1275405306&do=diff The Biological General Repository for Interaction Datasets (BioGRID) database (<http://www.thebiogrid.org>) was developed to house and distribute collections of protein and genetic interactions from major model organism species. BioGRID currently contains over 340,000 interactions from major model organism species, as derived from both high-throughput studies and conventional focused studies. Through comprehensive curation efforts, BioGRID now includes a virtually complete set of interactions re… text/html 2010-04-15T19:01:01-04:00 http://wiki.thebiogrid.org/doku.php/advanced_search?rev=1271372461&do=diff The following are advanced search options you can use to help better target the search results you're looking for: * Wildcard Searches - The BioGRID supports wildcard searching (ie. searching where the search is not exact but rather a range of possible matches) on the TAIL end of any keyword entered in our search field. To perform a wildcard search, simply enter your prefix (must be 3 letters or more) followed by a star (*). * Examples: STE*, CDC*, YAL01*, CLN* * These will not wor… text/html 2010-04-23T14:30:32-04:00 http://wiki.thebiogrid.org/doku.php/architecture?rev=1272047432&do=diff The BioGRID database architecture consists of three distinct components: (i) the Core (ii) the Web (iii) the Interaction Management System (IMS). This BioGRID data model was developed to be both extensible and modular. Each of the three components has a specific role in driving the BioGRID system and can easily be modified to meet rapidly changing needs in data management without entailing major changes to the applications it supports. In large databases, the integrity of the data model is often… text/html 2010-05-10T11:45:15-04:00 http://wiki.thebiogrid.org/doku.php/biogrid_tab_file_loader_plugin?rev=1273506315&do=diff This is an older version of our Plugin that is supported for legacy uses only. We recommend that you use our new BioGRID Plugin 2.0 for any new projects. Version 0.2 Update to accommodate new evidence codes 'Positive Genetic' and 'Negative Genetic'. text/html 2010-04-20T09:34:45-04:00 http://wiki.thebiogrid.org/doku.php/biogrid_tab_version_1.0?rev=1271770485&do=diff The BioGRID TAB 1.0 format is a custom BioGRID format that is designed to provide our curation efforts in a format that is simple to read in Microsoft Excel or to script into Bioinformatics applications. All Columns are separated by tabulations. This format is not recommended for new projects. Please use BioGRID Tab 2.0 files for new projects. text/html 2010-05-03T19:59:03-04:00 http://wiki.thebiogrid.org/doku.php/biogrid_tab_version_2.0?rev=1272931143&do=diff The BioGRID TAB 2.0 format is a custom BioGRID format that is designed to provide the entirety of our curation efforst in a format that is simple to read in Microsoft Excel or to script into Bioinformatics applications. All Columns are separated by tabulations. text/html 2010-05-10T09:43:33-04:00 http://wiki.thebiogrid.org/doku.php/biogridplugin2?rev=1273499013&do=diff BiogridPlugin2 is a plugin for the Cytoscape network visualization tool (<http://www.cytoscape.org>), designed to allow easy import of interactions from BioGRID data files. It is an update of the BiogridPlugin 0.2 release to allow import of data from our new tab2 file format. Additional features of BiogridPlugin2 include filtering of data during import based on gene lists and various interaction attributes, expanding of nodes and saving of networks in tab2 format. The plugin can be downloaded at… text/html 2010-04-19T20:43:07-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.17?rev=1271724187&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2790 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2790 1 Drosophila melanogaster PHYSICAL 22360 22178 7020 74 GENETIC 10340 2968 1194 1498 COMBINED 32700 25120 7506 1572 Homo sapiens PHYSICAL 38215 20974 7508 11934 GENETIC 0 … text/html 2010-04-19T20:41:57-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.18?rev=1271724117&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2790 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2790 1 Drosophila melanogaster PHYSICAL 22360 22178 7020 74 GENETIC 10340 2968 1194 1498 COMBINED 32700 25120 7506 1572 Homo sapiens PHYSICAL 38215 20974 7508 11934 GENETIC 0 … text/html 2010-04-19T20:40:29-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.19?rev=1271724029&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2790 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2790 1 Drosophila melanogaster PHYSICAL 22360 22178 7020 74 GENETIC 10340 2968 1194 1498 COMBINED 32700 25120 7506 1572 Homo sapiens PHYSICAL 38215 20974 7508 11934 GENETIC 0 … text/html 2010-04-19T20:35:07-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.20?rev=1271723707&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4432 4432 2786 1 GENETIC 0 0 0 0 COMBINED 4432 4432 2786 1 Drosophila melanogaster PHYSICAL 22171 22142 7000 3 GENETIC 10681 3039 1198 1512 COMBINED 32852 25155 7507 1515 Homo sapiens PHYSICAL 38215 20974 7508 11934 GENETIC 0 … text/html 2010-04-19T20:32:35-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.21?rev=1271723555&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4441 4441 2788 1 GENETIC 0 0 0 0 COMBINED 4441 4441 2788 1 Drosophila melanogaster PHYSICAL 22704 22428 7084 137 GENETIC 10685 3043 1199 1513 COMBINED 33389 25403 7546 1623 Homo sapiens PHYSICAL 38221 20979 7509 11934 GENETIC 0 … text/html 2010-04-19T20:30:45-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.22?rev=1271723445&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4441 4441 2788 1 GENETIC 0 0 0 0 COMBINED 4441 4441 2788 1 Drosophila melanogaster PHYSICAL 22704 22428 7084 137 GENETIC 10685 3043 1199 1513 COMBINED 33389 25403 7546 1623 Homo sapiens PHYSICAL 38230 20987 7514 11938 GENETIC 2 … text/html 2010-04-19T20:29:13-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.23?rev=1271723353&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4441 4441 2788 1 GENETIC 0 0 0 0 COMBINED 4441 4441 2788 1 Drosophila melanogaster PHYSICAL 22704 22428 7084 137 GENETIC 10685 3043 1199 1513 COMBINED 33389 25403 7546 1623 Homo sapiens PHYSICAL 38248 20996 7519 11946 GENETIC 2 … text/html 2010-04-19T20:29:25-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.24?rev=1271723365&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4441 4441 2788 1 GENETIC 0 0 0 0 COMBINED 4441 4441 2788 1 Drosophila melanogaster PHYSICAL 22704 22428 7084 137 GENETIC 10685 3043 1199 1513 COMBINED 33389 25403 7546 1623 Homo sapiens PHYSICAL 38248 20996 7519 11946 GENETIC 2 … text/html 2010-04-19T20:29:34-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.25?rev=1271723374&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38222 20980 7516 11941 GENETIC 3 … text/html 2010-04-19T20:29:46-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.26?rev=1271723386&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38222 20980 7516 11941 GENETIC 3 … text/html 2010-04-19T20:25:39-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.27?rev=1271723139&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38223 20981 7517 11942 GENETIC 4 … text/html 2010-04-19T20:24:59-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.28?rev=1271723099&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38221 20980 7517 11940 GENETIC 4 … text/html 2010-04-19T20:24:15-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.29?rev=1271723055&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38221 20980 7517 11940 GENETIC 4 … text/html 2010-04-19T20:18:18-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.30?rev=1271722698&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22765 22489 7086 137 GENETIC 10685 3043 1198 1513 COMBINED 33450 25464 7545 1623 Homo sapiens PHYSICAL 38221 20980 7517 11940 GENETIC 4 … text/html 2010-04-19T20:17:39-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.31?rev=1271722659&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22829 22522 7089 140 GENETIC 10689 3047 1199 1515 COMBINED 33518 25497 7546 1626 Homo sapiens PHYSICAL 38235 20988 7519 11944 GENETIC 4 … text/html 2010-04-19T20:16:39-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.32?rev=1271722599&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Caenorhabditis elegans PHYSICAL 4433 4433 2780 1 GENETIC 0 0 0 0 COMBINED 4433 4433 2780 1 Drosophila melanogaster PHYSICAL 22829 22522 7089 140 GENETIC 10689 3047 1199 1515 COMBINED 33518 25497 7546 1626 Homo sapiens PHYSICAL 38236 20989 7520 11945 GENETIC 4 … text/html 2010-04-19T20:15:58-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.33?rev=1271722558&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4670 4557 2816 8 GENETIC 861 858 654 3 COMBINED 5531 5414 3267 10 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 … text/html 2010-04-19T20:15:09-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.34?rev=1271722509&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4670 4557 2816 8 GENETIC 861 858 654 3 COMBINED 5531 5414 3267 10 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 … text/html 2010-04-19T20:14:25-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.35?rev=1271722465&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4670 4557 2816 8 GENETIC 2114 2083 1031 4 COMBINED 6784 6632 3524 11 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 … text/html 2010-04-19T18:37:17-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.36?rev=1271716637&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4670 4557 2816 8 GENETIC 2114 2083 1031 4 COMBINED 6784 6632 3524 11 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 … text/html 2010-04-19T18:36:02-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.37?rev=1271716562&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4670 4557 2816 8 GENETIC 2114 2083 1031 4 COMBINED 6784 6632 3524 11 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 … text/html 2010-04-19T18:34:59-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.38?rev=1271716499&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Caenorhabditis elegans PHYSICAL 4668 4555 2814 8 GENETIC 2114 2083 1031 4 COMBINED 6782 6630 3522 11 Canis familiaris PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 … text/html 2010-04-19T18:25:11-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.39?rev=1271715911&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2 2 3 1 GENETIC 0 0 0 0 COMBINED 2 2 3 1 Bos taurus PHYSICAL 2 2 4 2 GENETIC 0 0 0 0 COMBINED 2 2 4 2 Caenorhabditis elegans PHYSICAL 4668 4555 2814 8 GENETIC 2114 2083 1031 4 COMBINED 6782 6630 3522 11 … text/html 2010-04-19T18:19:11-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.40?rev=1271715551&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 209 134 88 30 GENETIC 101 56 39 27 COMBINED 310 186 111 53 Bos taurus PHYSICAL 2 2 4 2 GENETIC 0 0 0 0 COMBINED 2 2 4 2 Caenorhabditis elegans PHYSICAL 4668 4555 2814 8 GENETIC 2114 2083 1031 4 COMBINED 6782 6630… text/html 2010-04-19T18:18:32-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.41?rev=1271715512&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 590 360 295 143 GENETIC 154 95 69 52 COMBINED 744 443 327 186 Bos taurus PHYSICAL 4 4 7 3 GENETIC 0 0 0 0 COMBINED 4 4 7 3 Caenorhabditis elegans PHYSICAL 4668 4555 2814 8 GENETIC 2114 2083 1031 4 COMBINED 6782 6… text/html 2010-04-19T18:17:31-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.42?rev=1271715451&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 590 360 295 143 GENETIC 154 95 69 52 COMBINED 744 443 327 186 Bos taurus PHYSICAL 8 8 15 7 GENETIC 0 0 0 0 COMBINED 8 8 15 7 Caenorhabditis elegans PHYSICAL 4668 4555 2814 8 GENETIC 2114 2083 1031 4 COMBINED 6782 … text/html 2010-04-19T18:16:34-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.43?rev=1271715394&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 758 481 396 180 GENETIC 154 95 69 52 COMBINED 912 564 427 223 Bos taurus PHYSICAL 12 12 20 9 GENETIC 0 0 0 0 COMBINED 12 12 20 9 Caenorhabditis elegans PHYSICAL 4669 4556 2816 9 GENETIC 2114 2083 1031 4 COMBINED 678… text/html 2010-04-19T18:15:48-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.44?rev=1271715348&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 758 481 396 180 GENETIC 154 95 69 52 COMBINED 912 564 427 223 Bos taurus PHYSICAL 12 12 20 9 GENETIC 0 0 0 0 COMBINED 12 12 20 9 Caenorhabditis elegans PHYSICAL 4670 4557 2818 10 GENETIC 2114 2083 1031 4 COMBINED 67… text/html 2010-04-19T18:14:48-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.45?rev=1271715288&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 812 513 428 194 GENETIC 154 95 69 52 COMBINED 966 596 459 237 Bos taurus PHYSICAL 13 13 22 10 GENETIC 0 0 0 0 COMBINED 13 13 22 10 Caenorhabditis elegans PHYSICAL 4670 4557 2818 10 GENETIC 2114 2083 1031 4 COMBINED … text/html 2010-04-19T18:13:49-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.46?rev=1271715229&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1218 848 683 236 GENETIC 154 95 69 52 COMBINED 1372 931 711 279 Bos taurus PHYSICAL 13 13 22 10 GENETIC 0 0 0 0 COMBINED 13 13 22 10 Caenorhabditis elegans PHYSICAL 4670 4557 2818 10 GENETIC 2114 2083 1031 4 COMBINED … text/html 2010-04-19T18:11:34-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.47?rev=1271715094&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1218 848 683 236 GENETIC 154 95 69 52 COMBINED 1372 931 711 279 Bos taurus PHYSICAL 25 25 39 14 GENETIC 0 0 0 0 COMBINED 25 25 39 14 Caenorhabditis elegans PHYSICAL 4670 4557 2818 10 GENETIC 2114 2083 1031 4 COMBINED … text/html 2010-04-19T18:08:51-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.48?rev=1271714931&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1218 848 683 236 GENETIC 154 95 69 52 COMBINED 1372 931 711 279 Bos taurus PHYSICAL 51 42 60 21 GENETIC 0 0 0 0 COMBINED 51 42 60 21 Caenorhabditis elegans PHYSICAL 4672 4559 2821 12 GENETIC 2115 2084 1033 5 COMBINED … text/html 2010-04-19T18:07:51-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.49?rev=1271714871&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1265 885 712 247 GENETIC 154 95 69 52 COMBINED 1419 968 740 290 Bos taurus PHYSICAL 54 45 66 24 GENETIC 0 0 0 0 COMBINED 54 45 66 24 Caenorhabditis elegans PHYSICAL 4672 4559 2821 12 GENETIC 2115 2084 1033 5 COMBINED … text/html 2010-04-19T18:02:09-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.50?rev=1271714529&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1304 909 733 258 GENETIC 154 95 69 52 COMBINED 1458 991 761 301 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 60 49 71 25 GENETIC 0 0 0 0 COMBINED 60 49 71 25 … text/html 2010-04-19T18:01:24-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.51?rev=1271714484&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1355 960 774 260 GENETIC 154 95 69 52 COMBINED 1509 1042 801 303 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 60 49 71 25 GENETIC 0 0 0 0 COMBINED 60 49 71 25 … text/html 2010-04-19T18:00:32-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.52?rev=1271714432&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1362 964 778 262 GENETIC 154 95 69 52 COMBINED 1516 1046 805 305 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 60 49 71 25 GENETIC 0 0 0 0 COMBINED 60 49 71 25 … text/html 2010-04-19T17:59:32-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.53?rev=1271714372&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1362 964 778 262 GENETIC 154 95 69 52 COMBINED 1516 1046 805 305 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 62 50 73 26 GENETIC 0 0 0 0 COMBINED 62 50 73 26 … text/html 2010-04-19T17:58:29-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.54?rev=1271714309&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1583 1109 892 331 GENETIC 154 95 69 52 COMBINED 1737 1191 919 374 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 27… text/html 2010-04-19T17:57:38-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.55?rev=1271714258&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1664 1168 925 352 GENETIC 154 95 69 52 COMBINED 1818 1249 952 395 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 27… text/html 2010-04-19T17:56:14-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.56?rev=1271714174&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 1775 1240 969 386 GENETIC 154 95 69 52 COMBINED 1929 1321 996 429 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 27… text/html 2010-04-19T17:54:40-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.57?rev=1271714080&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 2556 1715 1196 513 GENETIC 154 95 69 52 COMBINED 2710 1793 1217 556 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 … text/html 2010-04-19T17:52:24-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.58?rev=1271713944&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 3704 2553 1501 641 GENETIC 154 95 69 52 COMBINED 3858 2631 1519 684 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 … text/html 2009-12-28T19:00:33-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.59?rev=1262044833&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 3902 2666 1584 681 GENETIC 154 95 69 52 COMBINED 4056 2744 1602 724 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 63 51 75 27 GENETIC 0 0 0 0 COMBINED 63 51 75 … text/html 2010-01-25T17:28:36-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.60?rev=1264458516&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 3929 2688 1600 688 GENETIC 154 95 69 52 COMBINED 4083 2766 1617 731 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-03-31T18:28:38-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.61?rev=1270074518&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 3986 2728 1617 698 GENETIC 154 95 69 52 COMBINED 4140 2806 1634 741 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-03-31T18:30:04-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.62?rev=1270074604&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4002 2738 1626 704 GENETIC 154 95 69 52 COMBINED 4156 2816 1643 747 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-04-24T10:02:41-04:00 http://wiki.thebiogrid.org/doku.php/build_2.0.63?rev=1272117761&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4061 2780 1653 714 GENETIC 154 95 69 52 COMBINED 4215 2858 1670 757 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-05-31T20:38:52-04:00 http://wiki.thebiogrid.org/doku.php/build_3.0.64?rev=1275352732&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4098 2798 1670 720 GENETIC 170 111 82 53 COMBINED 4268 2892 1700 764 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-06-21T10:18:59-04:00 http://wiki.thebiogrid.org/doku.php/build_3.0.65?rev=1277129939&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4652 3200 1712 734 GENETIC 172 113 85 54 COMBINED 4824 3295 1745 779 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-06-21T10:46:25-04:00 http://wiki.thebiogrid.org/doku.php/build_3.0.66?rev=1277131585&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4662 3207 1720 738 GENETIC 174 115 88 55 COMBINED 4836 3304 1755 783 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 64 52 77 28 GENETIC 0 0 0 0 COMBINED 64 52 77 … text/html 2010-07-31T05:23:19-04:00 http://wiki.thebiogrid.org/doku.php/build_3.0.67?rev=1280568199&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4719 3239 1735 747 GENETIC 174 115 88 55 COMBINED 4893 3336 1770 792 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 66 54 80 29 GENETIC 0 0 0 0 COMBINED 66 54 80 … text/html 2010-08-31T02:36:53-04:00 http://wiki.thebiogrid.org/doku.php/build_3.0.68?rev=1283236613&do=diff Organism Experiment Type Raw Interactions Non-Redundant Interactions Unique Proteins Unique Publications Arabidopsis thaliana PHYSICAL 4755 3257 1743 754 GENETIC 180 121 95 57 COMBINED 4935 3360 1785 801 Bacillus subtilis 168 PHYSICAL 1 1 2 1 GENETIC 0 0 0 0 COMBINED 1 1 2 1 Bos taurus PHYSICAL 66 54 80 29 GENETIC 0 0 0 0 COMBINED 66 54 80 … text/html 2010-04-23T13:25:05-04:00 http://wiki.thebiogrid.org/doku.php/contribute?rev=1272043505&do=diff In order for the BioGRID to continue to grow and expand, we rely on the community to help us through contributions that improve our dataset. There are 5 major ways that you can contribute right away. * Send us your published interaction data. * Join our curation team. * Link to us / Link to our result pages. * Alert us to publications that we might have missed in our curation. * Point out any errors/corrections to our existing data. text/html 2010-02-24T21:17:28-04:00 http://wiki.thebiogrid.org/doku.php/core?rev=1267064248&do=diff The BioGRID CORE is the largest component of the BioGRID architecture in terms of size and volume of data stored. It consistes of 26 tables that contain more than 74 million records. Our primary annotation information is stored and maintained in the CORE and is updated frequently from a large number of public resources including Entrez-Gene, UniprotKB, FlyBase, SGD, WormBase, MGD, OMIM, Ensembl, PSI, ZFIN, HPRD, TAIR, EcoCYC, PubCHEM, Pubmed, Gene Ontology, and more. The CORE is the foundation o… text/html 2009-12-23T11:43:56-04:00 http://wiki.thebiogrid.org/doku.php/curation_description?rev=1261586636&do=diff BioGRID curators capture experimental evidence supporting interactions from the primary literature. Our aim is to curate all interactions in the literature for major model organisms, and selective topic-driven human datasets. Interactions reported in reviews or as unpublished data are not recorded. The BioGRID curation workflow can be viewed [here]. text/html 2010-04-23T14:15:07-04:00 http://wiki.thebiogrid.org/doku.php/development_overview?rev=1272046507&do=diff All BioGRID-associated projects currently and will always make use of open source and openly available tools, programming languages, and databases for all software engineering projects. The following is a brief overview of the BioGRID development tools and process. text/html 2010-04-20T09:42:38-04:00 http://wiki.thebiogrid.org/doku.php/downloads?rev=1271770958&do=diff The BioGRID provides several file formats for download via our download (reached by clicking on downloads in the menu above) page. Each file format is outlined below with information on what types of information is available in each column and situations where you might want to use each. text/html 2010-04-20T09:38:44-04:00 http://wiki.thebiogrid.org/doku.php/experimental_systems?rev=1271770724&do=diff BioGRID interactions are recorded as relationships between two proteins or genes (i.e. they are binary relationships) with an evidence code that supports the interaction and a publication reference. The term “interaction” includes, as well as direct physical binding of two proteins, co-existence in a stable complex and genetic interaction. It should not be assumed that the interaction reported in BioGRID is direct and physical in nature; the experimental system definitions below indicate the n… text/html 2010-05-31T20:25:49-04:00 http://wiki.thebiogrid.org/doku.php/external_database_downloads?rev=1275351949&do=diff The following datasets are custom built specifically for processing by external database resources. If you did not request a dataset, you should NOT use any of these as they are not guaranteed to contain a full or up to date release of current BioGRID interaction data. Additionally, these datasets are subject to changes and modifications without notice, so there are zero guarantees that a given dataset will maintain its current format into the future. Otherwise, use at your own risk... text/html 2010-06-01T11:11:47-04:00 http://wiki.thebiogrid.org/doku.php/featured_datasets?rev=1275405107&do=diff The following datasets are either custom built by BioGRID or sent to us by contributers. These datasets are provided as is, and in some cases updated to correspond with our regular monthly updates. Please feel free to grab any of these datasets, but we highly recommend that you also consult the associated publication (if applicable) to get the most detail about how the set was compiled and how it may apply to your own requirements. text/html 2009-12-22T22:33:32-04:00 http://wiki.thebiogrid.org/doku.php/high_throughput_screens?rev=1261539212&do=diff As well as small-scale curated experiments, BioGRID contains data from papers reporting high throughput screens. Since the experimental setup of high throughput screens for interactions can be adjusted to give variable numbers of “hits”, it is common for publications to report a confidence score for each interaction. Before loading any high throughput data into BioGRID the data is assessed and interactions considered low confidence by the authors are not loaded. Generally, the confidence score … text/html 2010-06-24T08:21:16-04:00 http://wiki.thebiogrid.org/doku.php/highthroughput?rev=1277382076&do=diff Publications in biogrid with more than 100 interaction evidences are described in the table below. Those which have provided confidence scores or quantifiers for their interactions which have been loaded into BioGRID are indicated in the 'Score' column. For some publications, only a subset of all possible interactions have been loaded, based on a score cut-off suggested by the publication or authors. Where known this cut-off is described in the 'Comments' column. text/html 2010-08-24T07:52:36-04:00 http://wiki.thebiogrid.org/doku.php/identifiers?rev=1282650756&do=diff While we do support a wide variety of identifiers, our goal of limiting redundancy in our search results means that several large sequence databases such as Genbank and Ensembl do not have all their ID's available in the BioGRID. With each annotation update, our coverage increases by hundreds of thousands of new identifiers so please be patient if your ID is not currently supported. If you have a suggestion for a new identifier type, please let us know at <biogridadmin@gmail.com>. text/html 2010-04-23T14:32:03-04:00 http://wiki.thebiogrid.org/doku.php/interaction_management_system?rev=1272047523&do=diff The Interaction Management System or IMS is the component of the BioGRID Data Model that is directly accessed by our web-based curation tool-set. The IMS has been in production 6 years and has undergone several development cycles to enhance curation capabilities. The IMS is designed to enhance the curation process productivity and minimize human errors through consistent quality control and authentication of results, while at the same time supporting a multi-user environment with many curators o… text/html 2010-04-23T13:56:20-04:00 http://wiki.thebiogrid.org/doku.php/osprey_custom_network_version_1.3.1?rev=1272045380&do=diff The Osprey custom file format is a tab delimited text file that allows the user to load in a personal set of interactions data into the Osprey Network Visualization System. Osprey recognizes both a .txt and a .ocg extension for this file, but BioGRID will use the .txt extension for all downloads of this format. For more details on how to load an Osprey Custom Network, you can visit the Osprey documentation. text/html 2010-04-19T11:40:47-04:00 http://wiki.thebiogrid.org/doku.php/partners?rev=1271691647&do=diff In order to ensure that BioGRID data is available to as many users as possible, we work with many different partners in building tools, sharing interaction data, and collaborating on common curation goals. The following is a list of some of the different partners who work with us every day. If you're interested in becoming a BioGRID partner, please send us a message at <biogridadmin@gmail.com>. text/html 2009-12-24T00:04:41-04:00 http://wiki.thebiogrid.org/doku.php/privacy_policy?rev=1261631081&do=diff Introduction We at BioGRID and our affiliated companies worldwide are committed to respecting your online privacy and recognize your need for appropriate protection and management of any personally identifiable information (“Personal Information”) you share with us. text/html 2010-04-20T09:41:44-04:00 http://wiki.thebiogrid.org/doku.php/psi-mi_xml_version_1.0?rev=1271770904&do=diff The PSI MI format is a means of exchanging data on molecular interactions, maintained by the HUPO Proteomics Standards Initiative. For a diagram of the PSI 2.5 XML schema click here. BioGRID interactions are annotated with the terms described in the Experimental Evidence Codes section to distinguish between different types of evidence supporting an interaction. text/html 2010-04-20T09:55:14-04:00 http://wiki.thebiogrid.org/doku.php/psi-mi_xml_version_2.5?rev=1271771714&do=diff The PSI MI format is a means of exchanging data on molecular interactions, maintained by the HUPO Proteomics Standards Initiative. For a diagram of the PSI 2.5 XML schema click here. BioGRID interactions are annotated with the terms described in the Experimental Evidence Codes section to distinguish between different types of evidence supporting an interaction. The BioGRID PSI MI 2.5 XML files primarily contain MI ontology terms to describe experimental methods and other interaction details; pl… text/html 2010-03-16T16:27:29-04:00 http://wiki.thebiogrid.org/doku.php/psi_mitab_file?rev=1268771249&do=diff The MITAB format is part of the PSI-MI 2.5 standard. It is derived from the TAB 1.0 format provided by the BioGRID. MITAB only described binary interactions with one pair of interactions per row. Columns are separated by tabulations. Back to BioGRID Download Formats text/html 2010-06-11T04:10:33-04:00 http://wiki.thebiogrid.org/doku.php/results?rev=1276243833&do=diff The following is an example layout viewed when searching for your protein of interest within the BioGRID. We've outlined all areas of interest with yellow letters, and defined what each area represents in the definitions at the bottom of the page. text/html 2010-04-25T20:28:22-04:00 http://wiki.thebiogrid.org/doku.php/search_tips?rev=1272241702&do=diff The following are some suggestions that may help you find what you're looking for if you're having trouble searching: * Don't use ambiguous names. When possible, search for unique identifiers or systematic names. Many identifiers across the different species are duplicated, and as a result, may not uniquely identify a specific record. The more unique the identifier, the better your chance of getting a direct hit on searches. * Make sure the identifier you're searching for is supported. Ch… text/html 2010-05-10T10:43:10-04:00 http://wiki.thebiogrid.org/doku.php/start?rev=1273502590&do=diff While we try to provide as much documentation as possible about our site, we may overlook certain topics of interest. If you can't find the answer to your question listed in our support pages below, please email us at: <biogridadmin@gmail.com> and we will answer your question directly. Our site is constantly changing so please check back often for possible changes. text/html 2010-08-31T02:37:46-04:00 http://wiki.thebiogrid.org/doku.php/statistics?rev=1283236666&do=diff This page shows the latest snapshot of statistics for the BioGRID database. All previous snapshots are archived below separated by year. * Raw Interactions - Each unique combination of interactors A and B, experimental system and publication is counted as a single interaction. Reciprocal interactions (A → B and B → A) are counted twice. * Non-Redundant Interactions - Each unique combination of interactors A and B are counted as a single interaction, regardless of directionality, experim… text/html 2009-12-24T00:01:45-04:00 http://wiki.thebiogrid.org/doku.php/terms_and_conditions?rev=1261630905&do=diff 1. ACCEPTANCE OF TERMS BioGRID, provides the information and services on BioGRID sites to you, the user, conditioned upon your acceptance, without modification, of the terms and conditions of use (“Terms”) contained herein. Your use of BioGRID sites constitutes agreement with such Terms. text/html 2010-06-01T11:01:17-04:00 http://wiki.thebiogrid.org/doku.php/tools?rev=1275404477&do=diff Listed on this page are tools, software, and resources either written by the BioGRID team or a third party that can help you make use of BioGRID interaction data. All tools and resources are released WITHOUT ANY WARRANTY and are free to both academic and commercial entities for research purposes only. If you know of a useful software tool that should be in this listing, let us know at <biogridadmin@gmail.com>. text/html 2010-04-23T14:31:36-04:00 http://wiki.thebiogrid.org/doku.php/web?rev=1272047496&do=diff The BioGRID WEB Database (not to be confused with the World Wide Web) is a suite of tables engineered to drive our public BioGRID search interface. These tables are finely tuned to reduce the average response time required to return query results to the user over the internet. Each table has a specific function and derives all data from the CORE. These tables are used only for SQL SELECT queries, and are custom built and indexed to reduce the time required for common searches. The WEB is designe…