======= CRISPR Library Types and Names =======

===== CRISPR Library Types and Methodologies =====


^  Name  ^ Methodology       ^
^  CRISPRn  |Knockout: Generation of knockout cells or animals with loss-function mutations within the targeted genes.|
^  CRISPRa  |Activation: Use of CRISPR with a modified Cas enzyme fused to protein domains that turn gene expression on, thereby activating gene expression. |
^  CRISPRi  |Inhibition: Use of CRISPR with a modified Cas enzyme fused to protein domains that turn gene expression off, thereby repressing or inhibiting gene expression. |


===== CRISPR Library Names and Stats =====

^            Name            ^ Size ^ Addgene IDs^
^           Human            ^      ^^
^ GECKO                  |18,080|
^ GECKO v2               |19,050|AG cat #:1000000048, 1000000049|
^ SAM v1 (Zeomycin)      |23,430|AG cat #:1000000057|
^ SAM v1 (Puromycin)     |23,430|AG cat #:1000000075|
^ SAM v2 (bleomycin)     |23,430|AG cat #:1000000078|
^ CRISPRi-v2 (inhibition)|18,905|AG cat #:83969, 1000000090|
^ CRISPRa-v2 (activation)|18,915|AG cat #:83978, 1000000091|
^ Avana                  |18,675|
^ Brunello               |19,114|AG cat #:73179, 73178|
^ hCRISPRi-v2            |18,905|
^ hCRISPRa-v2            |23,430|
^ TKO (Toronto Knockout) v1|17,661|AG cat #:1000000069|
^ Toronto Knockout version 3 (TKOv3)|18,053|AG cat #:90294|
^ Edit-R crRNA Cell Cycle Regulation library|169|
^ Extended Knockout Library (EKO))|19,084|
^ Human Improved Genome-wide Knockout CRISPR Library|18,010|AG cat #:67989|
^ H1/H2 library (Liu Human CRISPR Knockout Library)|18,436|
^ Perturb-seq Guide Barcodes (GBC)|NA|AG cat #:85968|
^ Human CRISPR Knockout Pooled Libraries (Enriched Sub-pools)/(Wang, 2014)|7,114|AG cat #:51043-51048
^ CRISPRi (Weissman, 2014)|15,976|AG cat #:62217|
^ CRISPRa (Weissman, 2014)|15,977|AG cat #:60956|
^ Human Activity-Optimized CRISPR Knockout Library/CRISPRn (Wang, 2015)|18,166|AG cat #:1000000100|
^ CRISPRn (Deans, 2016)|18,509|
^ CRISPRn (DeJesus, 2016)|17,974|
^ CRISPRn Minipool (Goodwin, 2017)|1,120|
^ Bassik Human CRISPR Knockout Library|20,533|AG cat #:101926 — 101934|
^ CRISPRn (Wang, 2017)|18,663|
^ CRISPRn (Riba, 2017)|18,671|
^ CRISPRn (Potting, 2018)|18,703|
^ CRISPRn Targeted Library (Manguso, 2017)|2,368|
^ CRISPRn Targeted Library (Liao, 2018)|Unknown|
^ Human Kinase Domain-Focused CRISPR Knockout Library|482|AG cat #:117725
^ CRISPRn Targeted Transcription Factor Domain Library (Tarumoto, 2018)|1,427|
^ Focused Ras Synthetic Lethal Human CRISPR Knockout Library|132|AG cat #:92352|
^ Mini-human|Unspecified|AG cat #:130630|
^ Human CRISPR Library v.1.1|Unspecified|
^           Mouse            ^      ^^
^ GECKO v2 (mouse)                |20,611|AG cat #:1000000052,1000000053|
^ Mouse improved genome-wide library v2               |18,424|AG cat #:67988|
^ Bassik Mouse CRISPR Knockout Library     |22,414|AG cat #:1000000121 — 1000000130|
^ Murine lentiviral gRNA library (version 2)     |18,424|AG cat #:67988|
^ Mouse Two Plasmid Activity-Optimized CRISPR Knockout Library    |18,987|AG cat #:1000000096|
^ Murine lentiviral gRNA library (version 1)|19,149|AG cat #:50947|
^ Brie (mouse)|19,674|AG cat #:73632, 73633|
^ Asagio (mouse)                 |20,077|
^           Fly            ^      ^^
^ Oxford Fly|13,501|AG cat #:64750|
^ CRISPRn (Viswanatha, 2018) )|13,651|


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